製品: RAMP1 Antibody
カタログ: DF8597
タンパク質の説明: Rabbit polyclonal antibody to RAMP1
アプリケーション: WB
反応性: Human, Mouse, Rat
予測: Dog
分子量: 16 kDa; 17kD(Calculated).
ユニプロット: O60894
RRID: AB_2841801

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Dog(82%)
クローナリティ:
Polyclonal
特異性:
RAMP1 Antibody detects endogenous levels of total RAMP1.
RRID:
AB_2841801
引用形式: Affinity Biosciences Cat# DF8597, RRID:AB_2841801.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Calcitonin receptor like receptor activity modifying protein 1; Calcitonin-receptor-like receptor activity-modifying protein 1; CRLR activity modifying protein 1; CRLR activity-modifying protein 1; Ramp1; RAMP1_HUMAN; receptor (calcitonin) activity modifying protein 1; Receptor (G protein coupled) activity modifying protein 1; Receptor activity modifying protein 1 [Precursor]; Receptor activity-modifying protein 1;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
O60894 RAMP1_HUMAN:

Expressed in many tissues including the uterus, bladder, brain, pancreas and gastro-intestinal tract.

タンパク質配列:
MARALCRLPRRGLWLLLAHHLFMTTACQEANYGALLRELCLTQFQVDMEAVGETLWCDWGRTIRSYRELADCTWHMAEKLGCFWPNAEVDRFFLAVHGRYFRSCPISGRAVRDPPGSILYPFIVVPITVTLLVTALVVWQSKRTEGIV

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Dog
82
Horse
73
Pig
64
Bovine
64
Chicken
64
Xenopus
45
Sheep
0
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O60894 基板として

Site PTM Type Enzyme
Y100 Phosphorylation
S103 Phosphorylation
S107 Phosphorylation

研究背景

機能:

Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for calcitonin-gene-related peptide (CGRP) together with CALCRL.

細胞の位置付け:

Membrane>Single-pass type I membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in many tissues including the uterus, bladder, brain, pancreas and gastro-intestinal tract.

サブユニット構造:

Heterodimer of CALCRL and RAMP1.

タンパク質ファミリー:

Belongs to the RAMP family.

研究領域

· Organismal Systems > Circulatory system > Vascular smooth muscle contraction.   (View pathway)

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