Sec23B Antibody - #DF8607
| 製品: | Sec23B Antibody |
| カタログ: | DF8607 |
| タンパク質の説明: | Rabbit polyclonal antibody to Sec23B |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse |
| 予測: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 86 kDa; 86kD(Calculated). |
| ユニプロット: | Q15437 |
| RRID: | AB_2841811 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF8607, RRID:AB_2841811.
折りたたみ／展開
CDA II; CDAII; CDAN2; HEMPAS; Protein transport protein Sec23B; RP11-379J5.1; SC23B_HUMAN; Sec23 homolog B (S. cerevisiae); SEC23 related protein B; SEC23-like protein B; SEC23-related protein B; Sec23b; Transport protein SEC23B;
免疫原
- Q15437 SC23B_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MATYLEFIQQNEERDGVRFSWNVWPSSRLEATRMVVPLACLLTPLKERPDLPPVQYEPVLCSRPTCKAVLNPLCQVDYRAKLWACNFCFQRNQFPPAYGGISEVNQPAELMPQFSTIEYVIQRGAQSPLIFLYVVDTCLEEDDLQALKESLQMSLSLLPPDALVGLITFGRMVQVHELSCEGISKSYVFRGTKDLTAKQIQDMLGLTKPAMPMQQARPAQPQEHPFASSRFLQPVHKIDMNLTDLLGELQRDPWPVTQGKRPLRSTGVALSIAVGLLEGTFPNTGARIMLFTGGPPTQGPGMVVGDELKIPIRSWHDIEKDNARFMKKATKHYEMLANRTAANGHCIDIYACALDQTGLLEMKCCANLTGGYMVMGDSFNTSLFKQTFQRIFTKDFNGDFRMAFGATLDVKTSRELKIAGAIGPCVSLNVKGPCVSENELGVGGTSQWKICGLDPTSTLGIYFEVVNQHNTPIPQGGRGAIQFVTHYQHSSTQRRIRVTTIARNWADVQSQLRHIEAAFDQEAAAVLMARLGVFRAESEEGPDVLRWLDRQLIRLCQKFGQYNKEDPTSFRLSDSFSLYPQFMFHLRRSPFLQVFNNSPDESSYYRHHFARQDLTQSLIMIQPILYSYSFHGPPEPVLLDSSSILADRILLMDTFFQIVIYLGETIAQWRKAGYQDMPEYENFKHLLQAPLDDAQEILQARFPMPRYINTEHGGSQARFLLSKVNPSQTHNNLYAWGQETGAPILTDDVSLQVFMDHLKKLAVSSAC
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q15437 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| K67 | Ubiquitination | Uniprot | |
| K81 | Ubiquitination | Uniprot | |
| K185 | Ubiquitination | Uniprot | |
| K193 | Ubiquitination | Uniprot | |
| K198 | Ubiquitination | Uniprot | |
| K208 | Ubiquitination | Uniprot | |
| K260 | Ubiquitination | Uniprot | |
| K309 | Ubiquitination | Uniprot | |
| K320 | Acetylation | Uniprot | |
| K320 | Ubiquitination | Uniprot | |
| K331 | Ubiquitination | Uniprot | |
| Y333 | Phosphorylation | Uniprot | |
| K363 | Acetylation | Uniprot | |
| T381 | Phosphorylation | Uniprot | |
| S382 | Phosphorylation | Uniprot | |
| T393 | Phosphorylation | Uniprot | |
| K394 | Ubiquitination | Uniprot | |
| T407 | Phosphorylation | Uniprot | |
| T412 | Phosphorylation | Uniprot | |
| K431 | Ubiquitination | Uniprot | |
| K558 | Ubiquitination | Uniprot | |
| K564 | Ubiquitination | Uniprot | |
| K671 | Ubiquitination | Uniprot | |
| K684 | Ubiquitination | Uniprot | |
| S715 | Phosphorylation | Uniprot | |
| Y734 | Phosphorylation | Uniprot | |
| K760 | Ubiquitination | Uniprot |
研究背景
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex.
Cytoplasmic vesicle>COPII-coated vesicle membrane>Peripheral membrane protein>Cytoplasmic side. Endoplasmic reticulum membrane>Peripheral membrane protein>Cytoplasmic side. Cytoplasm>Cytosol.
Ubiquitously expressed.
COPII is composed of at least five proteins: the Sec23/24 complex, the Sec13/31 complex and Sar1 (By similarity). Interacts with SAR1A.
Belongs to the SEC23/SEC24 family. SEC23 subfamily.
研究領域
· Genetic Information Processing > Folding, sorting and degradation > Protein processing in endoplasmic reticulum. (View pathway)
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