SEI-1 Antibody - #DF8608
| 製品: | SEI-1 Antibody |
| カタログ: | DF8608 |
| タンパク質の説明: | Rabbit polyclonal antibody to SEI-1 |
| アプリケーション: | WB |
| 反応性: | Human |
| 予測: | Pig, Bovine, Sheep, Rabbit, Dog |
| 分子量: | 24 kDa; 25kD(Calculated). |
| ユニプロット: | Q9UHV2 |
| RRID: | AB_2841812 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF8608, RRID:AB_2841812.
折りたたみ／展開
CDK4 binding protein p34SEI; CDK4 binding protein p34SEI1; CDK4-binding protein p34SEI1; SEI-1; SEI1; SERTA domain containing 1; SERTA domain-containing protein 1; SERTAD1; SRTD1_HUMAN; Transcriptional regulator interacting with the PHD-bromodomain 1; TRIP Br1; TRIP-Br1;
免疫原
- Q9UHV2 SRTD1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLSKGLKRKREEEEEKEPLAVDSWWLDPGHTAVAQAPPAVASSSLFDLSVLKLHHSLQQSEPDLRHLVLVVNTLRRIQASMAPAAALPPVPSPPAAPSVADNLLASSDAALSASMASLLEDLSHIEGLSQAPQPLADEGPPGRSIGGAAPSLGALDLLGPATGCLLDDGLEGLFEDIDTSMYDNELWAPASEGLKPGPEDGPGKEEAPELDEAELDYLMDVLVGTQALERPPGPGR
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
研究背景
Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A.
Polyubiquitinated, which promotes proteasomal degradation.
Interacts with the PHD-bromodomain of TIF1, TRIM28/TIF1B and p300/CBP. Interacts with E2F1 and TFDP1; modulates transactivation activity of TFDP1/E2F complexes. Also interacts with CDK4.
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