製品: STEAP1 Antibody
カタログ: DF8618
タンパク質の説明: Rabbit polyclonal antibody to STEAP1
アプリケーション: WB IHC IF/ICC
反応性: Human, Rat
予測: Rabbit
分子量: 39 kDa; 40kD(Calculated).
ユニプロット: Q9UHE8
RRID: AB_2841822

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製品説明

ソース:
Rabbit
アプリケーション:
IF/ICC 1:100-1:500, WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Rat
予測:
Rabbit(100%)
クローナリティ:
Polyclonal
特異性:
STEAP1 Antibody detects endogenous levels of total STEAP1.
RRID:
AB_2841822
引用形式: Affinity Biosciences Cat# DF8618, RRID:AB_2841822.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

2410007B19Rik; EC 1.16.1.-; Metalloreductase STEAP1; MGC19484; PRSS 24; PRSS24; Six transmembrane epithelial antigen of prostate; Six transmembrane epithelial antigen of the prostate 1; Six transmembrane epithelial antigen of the prostate; Six-transmembrane epithelial antigen of prostate 1; STEA1_HUMAN; STEAP 1; Steap; STEAP1;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q9UHE8 STEA1_HUMAN:

Ubiquitously expressed. Highly expressed in prostate tumors.

タンパク質配列:
MESRKDITNQEELWKMKPRRNLEEDDYLHKDTGETSMLKRPVLLHLHQTAHADEFDCPSELQHTQELFPQWHLPIKIAAIIASLTFLYTLLREVIHPLATSHQQYFYKIPILVINKVLPMVSITLLALVYLPGVIAAIVQLHNGTKYKKFPHWLDKWMLTRKQFGLLSFFFAVLHAIYSLSYPMRRSYRYKLLNWAYQQVQQNKEDAWIEHDVWRMEIYVSLGIVGLAILALLAVTSIPSVSDSLTWREFHYIQSKLGIVSLLLGTIHALIFAWNKWIDIKQFVWYTPPTFMIAVFLPIVVLIFKSILFLPCLRKKILKIRHGWEDVTKINKTEICSQL

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Rabbit
100
Horse
75
Dog
63
Pig
0
Bovine
0
Sheep
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9UHE8 基板として

Site PTM Type Enzyme
Y27 Phosphorylation
K30 Ubiquitination
K39 Ubiquitination
T160 Phosphorylation
Y178 Phosphorylation
Y188 Phosphorylation
Y219 Phosphorylation
S221 Phosphorylation
K329 Ubiquitination
K332 Ubiquitination
S337 Phosphorylation

研究背景

機能:

Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor.

細胞の位置付け:

Endosome membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Ubiquitously expressed. Highly expressed in prostate tumors.

タンパク質ファミリー:

Belongs to the STEAP family.

研究領域

· Organismal Systems > Digestive system > Mineral absorption.

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