CD2 Tail-binding Antibody - #DF8644
| 製品: | CD2 Tail-binding Antibody |
| カタログ: | DF8644 |
| タンパク質の説明: | Rabbit polyclonal antibody to CD2 Tail-binding |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 37 kDa; 38kD(Calculated). |
| ユニプロット: | O95400 |
| RRID: | AB_2841848 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF8644, RRID:AB_2841848.
折りたたみ／展開
CD2 (cytoplasmic tail) binding protein 2; CD2 antigen (cytoplasmic tail) binding protein 2; CD2 antigen cytoplasmic tail-binding protein 2; CD2 cytoplasmic domain-binding protein 2; CD2 tail-binding protein 2; CD2B2_HUMAN; Cd2bp2; FWP010; LIN1; Snu40; U5 snRNP 52K protein; U5-52K;
免疫原
- O95400 CD2B2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPKRKVTFQGVGDEEDEDEIIVPKKKLVDPVAGSGGPGSRFKGKHSLDSDEEEDDDDGGSSKYDILASEDVEGQEAATLPSEGGVRITPFNLQEEMEEGHFDADGNYFLNRDAQIRDSWLDNIDWVKIRERPPGQRQASDSEEEDSLGQTSMSAQALLEGLLELLLPRETVAGALRRLGARGGGKGRKGPGQPSSPQRLDRLSGLADQMVARGNLGVYQETRERLAMRLKGLGCQTLGPHNPTPPPSLDMFAEELAEEELETPTPTQRGEAESRGDGLVDVMWEYKWENTGDAELYGPFTSAQMQTWVSEGYFPDGVYCRKLDPPGGQFYNSKRIDFDLYT
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O95400 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T7 | Phosphorylation | Uniprot | |
| K24 | Ubiquitination | Uniprot | |
| K26 | Sumoylation | Uniprot | |
| S34 | Phosphorylation | Uniprot | |
| S46 | Phosphorylation | Uniprot | |
| S49 | Phosphorylation | Uniprot | |
| S60 | Phosphorylation | Uniprot | |
| S61 | Phosphorylation | Uniprot | |
| Y107 | Phosphorylation | Uniprot | |
| S118 | Phosphorylation | Uniprot | |
| K127 | Ubiquitination | Uniprot | |
| S139 | Phosphorylation | Uniprot | |
| S141 | Phosphorylation | Uniprot | |
| T150 | Phosphorylation | Uniprot | |
| S151 | Phosphorylation | Uniprot | |
| R176 | Methylation | Uniprot | |
| R181 | Methylation | Uniprot | |
| S194 | Phosphorylation | Uniprot | |
| S195 | Phosphorylation | Uniprot | |
| T243 | Phosphorylation | Uniprot | |
| S247 | Phosphorylation | Uniprot | |
| T262 | Phosphorylation | Uniprot | |
| K321 | Sumoylation | Uniprot | |
| K321 | Ubiquitination | Uniprot | |
| Y330 | Phosphorylation | Uniprot | |
| S332 | Phosphorylation | Uniprot | |
| K333 | Acetylation | Uniprot | |
| K333 | Ubiquitination | Uniprot | |
| T341 | Phosphorylation | Uniprot |
研究背景
Involved in pre-mRNA splicing as component of the U5 snRNP complex that is involved in spliceosome assembly.
Cytoplasm. Nucleus.
Note: Predominantly nuclear.
Component of the U5 snRNP complex composed of the U5 snRNA and at least PRPF6, PRPF8, SNRNP200, EFTUD2, SNRNP40, DDX23, TXNL4A and CD2BP2. Interacts directly with TXNL4A and PRPF6. Interacts (via GYF domain) with CD2 (via Pro-rich sequence in the cytoplasmic domain). Interacts with PQBP1.
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