MDM1 Antibody - #DF8676
| 製品: | MDM1 Antibody |
| カタログ: | DF8676 |
| タンパク質の説明: | Rabbit polyclonal antibody to MDM1 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig |
| 分子量: | 80 kDa; 81kD(Calculated). |
| ユニプロット: | Q8TC05 |
| RRID: | AB_2841880 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF8676, RRID:AB_2841880.
折りたたみ／展開
FLJ95264; MDM 1; Mdm1; Mdm1 nuclear protein homolog (mouse); Mdm1 nuclear protein homolog; MDM1_HUMAN; Mdm4 transformed 3T3 cell double minute 1 p53 binding protein (mouse); Mdm4 transformed 3T3 cell double minute 1 p53 binding protein; Mouse Mdm1 nuclear protein homolog; Nuclear protein double minute 1; Nuclear protein MDM1;
免疫原
- Q8TC05 MDM1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPVRFKGLSEYQRNFLWKKSYLSESCNSSVGRKYPWAGLRSDQLGITKEPSFISKRRVPYHDPQISKSLEWNGAISESNVVASPEPEAPETPKSQEAEQKDVTQERVHSLEASRVPKRTRSHSADSRAEGASDVENNEGVTNHTPVNENVELEHSTKVLSENVDNGLDRLLRKKAGLTVVPSYNALRNSEYQRQFVWKTSKETAPAFAANQVFHNKSQFVPPFKGNSVIHETEYKRNFKGLSPVKEPKLRNDLRENRNLETVSPERKSNKIDDRLKLEAEMELKDLHQPKRKLTPWKHQRLGKVNSEYRAKFLSPAQYLYKAGAWTHVKGNMPNQVKELREKAEFYRKRVQGTHFSRDHLNQILSDSNCCWDVSSTTSSEGTVSSNIRALDLAGDPTSHKTLQKCPSTEPEEKGNIVEEQPQKNTTEKLGVSAPTIPVRRRLAWDTENTSEDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKADKMKEGSDSSVSSEKGGRLPTPKLRELGGIQRTHHDLTTPAVGGAVLVSPSKMKPPAPEQRKRMTSQDCLETSKNDFTKKESRAVSLLTSPAAGIKTVDPLPLREDSEDNIHKFAEATLPVSKIPKYPTNPPGQLPSPPHVPSYWHPSRRIQGSLRDPEFQHNVGKARMNNLQLPQHEAFNDEDEDRLSEISARSAASSLRAFQTLARAKKRKENFWGKT
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q8TC05 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K6 | Methylation | Uniprot | |
| S29 | Phosphorylation | Uniprot | |
| K48 | Ubiquitination | Uniprot | |
| S51 | Phosphorylation | Uniprot | |
| S83 | Phosphorylation | Uniprot | |
| S109 | Phosphorylation | Uniprot | |
| S132 | Phosphorylation | Uniprot | |
| Y234 | Phosphorylation | Uniprot | |
| S242 | Phosphorylation | Uniprot | |
| S263 | Phosphorylation | Uniprot | |
| T294 | Phosphorylation | Uniprot | |
| K297 | Ubiquitination | Uniprot | |
| S314 | Phosphorylation | Uniprot | |
| S356 | Phosphorylation | Uniprot | |
| T408 | Phosphorylation | Uniprot | |
| S503 | Phosphorylation | Uniprot | |
| S504 | Phosphorylation | Uniprot | |
| S506 | Phosphorylation | Uniprot | |
| T515 | Phosphorylation | Uniprot | |
| S543 | Phosphorylation | Uniprot | |
| T572 | Phosphorylation | Uniprot | |
| K573 | Methylation | Uniprot | |
| K574 | Methylation | Uniprot | |
| S584 | Phosphorylation | Uniprot | |
| K590 | Ubiquitination | Uniprot | |
| S601 | Phosphorylation | Uniprot | |
| S631 | Phosphorylation | Uniprot | |
| S648 | Phosphorylation | Uniprot | |
| S683 | Phosphorylation | Uniprot | |
| S686 | Phosphorylation | Uniprot |
研究背景
Microtubule-binding protein that negatively regulates centriole duplication. Binds to and stabilizes microtubules.
Nucleus. Cytoplasm>Cytoskeleton>Microtubule organizing center>Centrosome. Cytoplasm>Cytoskeleton>Microtubule organizing center>Centrosome>Centriole.
Note: Localizes to the centriole lumen.
Belongs to the MDM1 family.
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