RELT Antibody - #DF8712
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF8712, RRID:AB_2841916.
折りたたみ／展開
Receptor expressed in lymphoid tissues; Relt; TNFRSF19L; TR19L_HUMAN; Tumor necrosis factor receptor superfamily member 19L;
免疫原
Spleen, lymph node, brain, breast and peripheral blood leukocytes (at protein level) (PubMed:28688764). Expressed highly in bone marrow and fetal liver. Very low levels in skeletal muscle, testis and colon. Not detected in kidney and pancreas.
- Q969Z4 TR19L_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKPSLLCRPLSCFLMLLPWPLATLTSTTLWQCPPGEEPDLDPGQGTLCRPCPPGTFSAAWGSSPCQPHARCSLWRRLEAQVGMATRDTLCGDCWPGWFGPWGVPRVPCQPCSWAPLGTHGCDEWGRRARRGVEVAAGASSGGETRQPGNGTRAGGPEETAAQYAVIAIVPVFCLMGLLGILVCNLLKRKGYHCTAHKEVGPGPGGGGSGINPAYRTEDANEDTIGVLVRLITEKKENAAALEELLKEYHSKQLVQTSHRPVSKLPPAPPNVPHICPHRHHLHTVQGLASLSGPCCSRCSQKKWPEVLLSPEAVAATTPVPSLLPNPTRVPKAGAKAGRQGEITILSVGRFRVARIPEQRTSSMVSEVKTITEAGPSWGDLPDSPQPGLPPEQQALLGSGGSRTKWLKPPAENKAEENRYVVRLSESNLVI
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q969Z4 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S140 | Phosphorylation | Uniprot | |
| Y214 | Phosphorylation | Uniprot | |
| T223 | Phosphorylation | Uniprot | |
| K235 | Ubiquitination | Uniprot | |
| K246 | Ubiquitination | Uniprot | |
| K251 | Ubiquitination | Uniprot | |
| S299 | Phosphorylation | Uniprot | |
| S309 | Phosphorylation | Uniprot | |
| T317 | Phosphorylation | Uniprot | |
| S321 | Phosphorylation | Uniprot | |
| T327 | Phosphorylation | Uniprot | |
| K404 | Ubiquitination | Uniprot |
研究背景
May play a role in apoptosis. Induces activation of MAPK14/p38 and MAPK8/JNK MAPK cascades, when overexpressed. Involved in dental enamel formation.
Phosphorylated in vitro by OXSR1. Phosphorylated by STK39.
Cell membrane>Single-pass type I membrane protein. Cytoplasm. Cytoplasm>Perinuclear region.
Spleen, lymph node, brain, breast and peripheral blood leukocytes (at protein level). Expressed highly in bone marrow and fetal liver. Very low levels in skeletal muscle, testis and colon. Not detected in kidney and pancreas.
Interacts with TRAF1. Interacts with RELL1, RELL2 and OXSR1. Interacts with PLSCR1. Interacts with STK39.
Belongs to the RELT family.
研究領域
· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction. (View pathway)
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