TTF1 Antibody - #DF8830
| 製品: | TTF1 Antibody |
| カタログ: | DF8830 |
| タンパク質の説明: | Rabbit polyclonal antibody to TTF1 |
| アプリケーション: | WB IHC |
| 反応性: | Human, Rat |
| 予測: | Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 103 kDa; 103kD(Calculated). |
| ユニプロット: | Q15361 |
| RRID: | AB_2842027 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF8830, RRID:AB_2842027.
折りたたみ／展開
RNA polymerase I termination factor; Transcription termination factor 1; Transcription termination factor I; Transcription termination factor RNA polymerase I; TTF 1; TTF-1; TTF-I; Ttf1; TTF1_HUMAN;
免疫原
- Q15361 TTF1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEGESSRFEIHTPVSDKKKKKCSIHKERPQKHSHEIFRDSSLVNEQSQITRRKKRKKDFQHLISSPLKKSRICDETANATSTLKKRKKRRYSALEVDEEAGVTVVLVDKENINNTPKHFRKDVDVVCVDMSIEQKLPRKPKTDKFQVLAKSHAHKSEALHSKVREKKNKKHQRKAASWESQRARDTLPQSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQESRPAVGLHGETAGIPAPAYKNKSKKKKKKSNHQEFEAVAMPESLESAYPEGSQVGSEVGTVEGSTALKGFKESNSTKKKSKKRKLTSVKRARVSGDDFSVPSKNSESTLFDSVEGDGAMMEEGVKSRPRQKKTQACLASKHVQEAPRLEPANEEHNVETAEDSEIRYLSADSGDADDSDADLGSAVKQLQEFIPNIKDRATSTIKRMYRDDLERFKEFKAQGVAIKFGKFSVKENKQLEKNVEDFLALTGIESADKLLYTDRYPEEKSVITNLKRRYSFRLHIGRNIARPWKLIYYRAKKMFDVNNYKGRYSEGDTEKLKMYHSLLGNDWKTIGEMVARSSLSVALKFSQISSQRNRGAWSKSETRKLIKAVEEVILKKMSPQELKEVDSKLQENPESCLSIVREKLYKGISWVEVEAKVQTRNWMQCKSKWTEILTKRMTNGRRIYYGMNALRAKVSLIERLYEINVEDTNEIDWEDLASAIGDVPPSYVQTKFSRLKAVYVPFWQKKTFPEIIDYLYETTLPLLKEKLEKMMEKKGTKIQTPAAPKQVFPFRDIFYYEDDSEGEDIEKESEGQAPCMAHACNSSTLGGQGRWII
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q15361 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T12 | Phosphorylation | Uniprot | |
| S15 | Phosphorylation | Uniprot | |
| S41 | Phosphorylation | Uniprot | |
| S47 | Phosphorylation | Uniprot | |
| S64 | Phosphorylation | Uniprot | |
| S65 | Phosphorylation | Uniprot | |
| S81 | Phosphorylation | Uniprot | |
| T82 | Phosphorylation | Uniprot | |
| K84 | Ubiquitination | Uniprot | |
| K144 | Ubiquitination | Uniprot | |
| K150 | Ubiquitination | Uniprot | |
| S161 | Phosphorylation | Uniprot | |
| S177 | Phosphorylation | Uniprot | |
| S213 | Phosphorylation | Uniprot | |
| S227 | Phosphorylation | Uniprot | |
| Y231 | Phosphorylation | Uniprot | |
| S240 | Phosphorylation | Uniprot | |
| T248 | Phosphorylation | Uniprot | |
| S253 | Phosphorylation | Uniprot | |
| T263 | Phosphorylation | Uniprot | |
| S297 | Phosphorylation | Uniprot | |
| S301 | Phosphorylation | Uniprot | |
| Y357 | Phosphorylation | Uniprot | |
| S361 | Phosphorylation | Uniprot | |
| S365 | Phosphorylation | Uniprot | |
| K398 | Acetylation | Uniprot | |
| S403 | Phosphorylation | Uniprot | |
| K434 | Ubiquitination | Uniprot | |
| K449 | Acetylation | Uniprot | |
| K449 | Ubiquitination | Uniprot | |
| S472 | Phosphorylation | Uniprot | |
| Y476 | Phosphorylation | Uniprot | |
| S478 | Phosphorylation | Uniprot | |
| S481 | Phosphorylation | Uniprot | |
| S487 | Phosphorylation | Uniprot | |
| K506 | Ubiquitination | Uniprot | |
| K514 | Ubiquitination | Uniprot | |
| K528 | Methylation | Uniprot | |
| K528 | Ubiquitination | Uniprot | |
| K538 | Ubiquitination | Uniprot | |
| K542 | Ubiquitination | Uniprot | |
| K549 | Ubiquitination | Uniprot | |
| K565 | Ubiquitination | Uniprot | |
| K583 | Ubiquitination | Uniprot | |
| K617 | Ubiquitination | Uniprot | |
| S621 | Phosphorylation | Uniprot | |
| K627 | Ubiquitination | Uniprot | |
| K629 | Ubiquitination | Uniprot | |
| K640 | Ubiquitination | Uniprot | |
| S650 | Phosphorylation | Uniprot | |
| K671 | Ubiquitination | Uniprot | |
| K688 | Acetylation | Uniprot | |
| S690 | Phosphorylation | Uniprot | |
| K695 | Ubiquitination | Uniprot | |
| K700 | Acetylation | Uniprot | |
| K700 | Ubiquitination | Uniprot | |
| S710 | Phosphorylation | Uniprot | |
| K738 | Ubiquitination | Uniprot | |
| K740 | Ubiquitination | Uniprot | |
| K747 | Ubiquitination | Uniprot | |
| K765 | Ubiquitination | Uniprot | |
| K808 | Ubiquitination | Uniprot | |
| K838 | Ubiquitination | Uniprot | |
| K857 | Acetylation | Uniprot | |
| K857 | Ubiquitination | Uniprot | |
| Y868 | Phosphorylation | Uniprot | |
| S872 | Phosphorylation | Uniprot |
研究背景
Multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. Plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5 recovers DNA-binding activity.
Nucleus. Nucleus>Nucleolus.
Oligomer. The oligomeric structure enables to interact simultaneously with two separate DNA fragments. Interacts with BAZ2A/TIP5. Interacts with CAVIN1.
The N-terminal region (NRD) inhibits DNA-binding via its interaction with the C-terminal region.
研究領域
· Organismal Systems > Endocrine system > Thyroid hormone synthesis.
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