製品: ZMAT3 Antibody
カタログ: DF8871
タンパク質の説明: Rabbit polyclonal antibody to ZMAT3
アプリケーション: WB
反応性: Human, Mouse
予測: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
分子量: 32 kDa; 32kD(Calculated).
ユニプロット: Q9HA38
RRID: AB_2842067

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 100ul $280 在庫あり
 200ul $350 在庫あり

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
予測:
Pig(100%), Zebrafish(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(91%)
クローナリティ:
Polyclonal
特異性:
ZMAT3 Antibody detects endogenous levels of total ZMAT3.
RRID:
AB_2842067
引用形式: Affinity Biosciences Cat# DF8871, RRID:AB_2842067.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

FLJ12296; FLJ31683; MGC10613; OTTHUMP00000211906; OTTHUMP00000211907; p53 activated gene 608; p53 inducible zinc finger protein; p53 target zinc finger protein; p53-activated gene 608 protein; PAG 608; WIG 1; WIG 1/PAG608 protein; WIG1; WIG1/PAG608 protein; Wildtype p53-induced gene; Zinc finger matrin type 3; Zinc finger matrin-type protein 3; Zinc finger protein WIG 1; Zinc finger protein WIG-1; Zinc finger protein WIG1; ZMAT 3; Zmat3; ZMAT3_HUMAN;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q9HA38 ZMAT3_HUMAN:

Highly expressed in adult brain, and moderately in adult kidney and testis. Not detected in fetal brain, heart, pancreas, adrenal gland, liver or small intestine.

タンパク質配列:
MILLQHAVLPPPKQPSPSPPMSVATRSTGTLQLPPQKPFGQEASLPLAGEEELSKGGEQDCALEELCKPLYCKLCNVTLNSAQQAQAHYQGKNHGKKLRNYYAANSCPPPARMSNVVEPAATPVVPVPPQMGSFKPGGRVILATENDYCKLCDASFSSPAVAQAHYQGKNHAKRLRLAEAQSNSFSESSELGQRRARKEGNEFKMMPNRRNMYTVQNNSAGPYFNPRSRQRIPRDLAMCVTPSGQFYCSMCNVGAGEEMEFRQHLESKQHKSKVSEQRYRNEMENLGYV

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Zebrafish
100
Chicken
100
Rabbit
100
Xenopus
91
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9HA38 基板として

Site PTM Type Enzyme
S16 Phosphorylation
Y89 Phosphorylation
S158 Phosphorylation
S182 Phosphorylation
S184 Phosphorylation
K198 Ubiquitination
T214 Phosphorylation
K268 Ubiquitination

研究背景

機能:

Acts as a bona fide target gene of p53/TP53. May play a role in the TP53-dependent growth regulatory pathway. May contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation to the nucleus and nucleolus.

細胞の位置付け:

Nucleus. Nucleus>Nucleolus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Highly expressed in adult brain, and moderately in adult kidney and testis. Not detected in fetal brain, heart, pancreas, adrenal gland, liver or small intestine.

サブユニット構造:

Interacts with dsRNA.

研究領域

· Cellular Processes > Cell growth and death > p53 signaling pathway.   (View pathway)

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