製品: BMP2K Antibody
カタログ: DF8878
タンパク質の説明: Rabbit polyclonal antibody to BMP2K
アプリケーション: WB
反応性: Human, Mouse, Rat
予測: Pig, Zebrafish, Rabbit, Dog
分子量: 129 kDa; 129kD(Calculated).
ユニプロット: Q9NSY1
RRID: AB_2842074

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Zebrafish(92%), Rabbit(100%), Dog(100%)
クローナリティ:
Polyclonal
特異性:
BMP2K Antibody detects endogenous levels of total BMP2K.
RRID:
AB_2842074
引用形式: Affinity Biosciences Cat# DF8878, RRID:AB_2842074.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

BIKe; Bike kinase; BMP 2 inducible protein kinase; BMP-2-inducible protein kinase; BMP2 inducible kinase; BMP2 inducible protein kinase; BMP2K; BMP2K_HUMAN; DKFZp434K0614; DKFZp434P0116; HRIHFB2017;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MKKFSRMPKSEGGSGGGAAGGGAGGAGAGAGCGSGGSSVGVRVFAVGRHQVTLEESLAEGGFSTVFLVRTHGGIRCALKRMYVNNMPDLNVCKREITIMKELSGHKNIVGYLDCAVNSISDNVWEVLILMEYCRAGQVVNQMNKKLQTGFTEPEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLNDGGNYVLCDFGSATNKFLNPQKDGVNVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLPFGESQVAICDGNFTIPDNSRYSRNIHCLIRFMLEPDPEHRPDIFQVSYFAFKFAKKDCPVSNINNSSIPSALPEPMTASEAAARKSQIKARITDTIGPTETSIAPRQRPKANSATTATPSVLTIQSSATPVKVLAPGEFGNHRPKGALRPGNGPEILLGQGPPQQPPQQHRVLQQLQQGDWRLQQLHLQHRHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQMLQQQFLMHSVYQPQPSASQYPTMMPQYQQAFFQQQMLAQHQPSQQQASPEYLTSPQEFSPALVSYTSSLPAQVGTIMDSSYSANRSVADKEAIANFTNQKNISNPPDMSGWNPFGEDNFSKLTEEELLDREFDLLRSNRLEERASSDKNVDSLSAPHNHPPEDPFGSVPFISHSGSPEKKAEHSSINQENGTANPIKNGKTSPASKDQRTGKKTSVQGQVQKGNDESESDFESDPPSPKSSEEEEQDDEEVLQGEQGDFNDDDTEPENLGHRPLLMDSEDEEEEEKHSSDSDYEQAKAKYSDMSSVYRDRSGSGPTQDLNTILLTSAQLSSDVAVETPKQEFDVFGAVPFFAVRAQQPQQEKNEKNLPQHRFPAAGLEQEEFDVFTKAPFSKKVNVQECHAVGPEAHTIPGYPKSVDVFGSTPFQPFLTSTSKSESNEDLFGLVPFDEITGSQQQKVKQRSLQKLSSRQRRTKQDMSKSNGKRHHGTPTSTKKTLKPTYRTPERARRHKKVGRRDSQSSNEFLTISDSKENISVALTDGKDRGNVLQPEESLLDPFGAKPFHSPDLSWHPPHQGLSDIRADHNTVLPGRPRQNSLHGSFHSADVLKMDDFGAVPFTELVVQSITPHQSQQSQPVELDPFGAAPFPSKQ

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Dog
100
Rabbit
100
Zebrafish
92
Horse
0
Bovine
0
Sheep
0
Xenopus
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9NSY1 基板として

Site PTM Type Enzyme
S14 Phosphorylation
K93 Ubiquitination
K173 Ubiquitination
K182 Ubiquitination
K211 Ubiquitination
K222 Ubiquitination
K223 Ubiquitination
K241 Ubiquitination
Y257 Phosphorylation
S378 Phosphorylation
T383 Phosphorylation
T394 Phosphorylation
Y594 Phosphorylation
K613 Ubiquitination
S616 Phosphorylation
S665 Phosphorylation
S680 Phosphorylation
S689 Phosphorylation
S715 Phosphorylation
S728 Phosphorylation
S740 Phosphorylation
S742 Phosphorylation
S791 Phosphorylation
Y813 Phosphorylation
S817 Phosphorylation
S818 Phosphorylation
Y820 Phosphorylation
S824 Phosphorylation
S826 Phosphorylation
T829 Phosphorylation
T834 Phosphorylation
S843 Phosphorylation
S928 Phosphorylation
T935 Phosphorylation
S945 Phosphorylation
S947 Phosphorylation
S949 Phosphorylation
S974 Phosphorylation
S979 Phosphorylation
S980 Phosphorylation
K991 Ubiquitination
T1002 Phosphorylation
T1011 Phosphorylation
Y1012 Phosphorylation
T1014 Phosphorylation
S1029 Phosphorylation
S1031 Phosphorylation
S1032 Phosphorylation
T1037 Phosphorylation
S1039 Phosphorylation
S1041 Phosphorylation
S1046 Phosphorylation
S1076 Phosphorylation
S1080 Phosphorylation
S1089 Phosphorylation
T1097 Phosphorylation
S1107 Phosphorylation
S1111 Phosphorylation
S1114 Phosphorylation

研究背景

機能:

May be involved in osteoblast differentiation.

PTMs:

Autophosphorylated.

細胞の位置付け:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
タンパク質ファミリー:

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

研究領域

· Human Diseases > Cancers: Overview > Transcriptional misregulation in cancer.

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