製品: DRD1IP Antibody
カタログ: DF8939
タンパク質の説明: Rabbit polyclonal antibody to DRD1IP
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse
予測: Rabbit, Dog
分子量: 23 kDa; 23kD(Calculated).
ユニプロット: Q9NYX4
RRID: AB_2842135

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
予測:
Rabbit(100%), Dog(100%)
クローナリティ:
Polyclonal
特異性:
DRD1IP Antibody detects endogenous levels of total DRD1IP.
RRID:
AB_2842135
引用形式: Affinity Biosciences Cat# DF8939, RRID:AB_2842135.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

CALCYON; Caly; CALY_HUMAN; D1 dopamine receptor interacting protein; Drd1ip; Neuron specific vesicular protein calcyon; Neuron-specific vesicular protein calcyon; NSG3; RP11-122K13.5;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q9NYX4 CALY_HUMAN:

Expressed in the pyramidal cells of the prefrontal cortex, in hippothalamus and in caudate nucleus. No expression in spleen. Up-regulated in the prefrontal cortex of schizophrenic patients with nearly twice the levels of non-schizophrenics.

タンパク質配列:
MVKLGCSFSGKPGKDPGDQDGAAMDSVPLISPLDISQLQPPLPDQVVIKTQTEYQLSSPDQQNFPDLEGQRLNCSHPEEGRRLPTARMIAFAMALLGCVLIMYKAIWYDQFTCPDGFLLRHKICTPLTLEMYYTEMDPERHRSILAAIGAYPLSRKHGTETPAAWGDGYRAAKEERKGPTQAGAAAAATEPPGKPSAKAEKEAARKAAGSAAPPPAQ

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Rabbit
100
Dog
100
Pig
75
Bovine
75
Sheep
75
Horse
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9NYX4 基板として

Site PTM Type Enzyme

研究背景

機能:

Interacts with clathrin light chain A and stimulates clathrin self-assembly and clathrin-mediated endocytosis.

PTMs:

Glycosylated.

細胞の位置付け:

Cytoplasmic vesicle membrane>Single-pass membrane protein. Cell membrane>Single-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in the pyramidal cells of the prefrontal cortex, in hippothalamus and in caudate nucleus. No expression in spleen. Up-regulated in the prefrontal cortex of schizophrenic patients with nearly twice the levels of non-schizophrenics.

サブユニット構造:

Interacts with CLTA.

タンパク質ファミリー:

Belongs to the NSG family.

研究領域

· Organismal Systems > Nervous system > Dopaminergic synapse.

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