ICBR Antibody - #DF8960
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF8960, RRID:AB_2842156.
折りたたみ／展開
CAR18_HUMAN; CARD18; Caspase 1 inhibitor Iceberg; Caspase recruitment domain family member 18; Caspase recruitment domain-containing protein 18; Caspase-1 inhibitor Iceberg; ICEBERG caspase 1 inhibitor; Pseudo ICE; UNQ5804; UNQ5804/PRO19611;
免疫原
- P57730 CAR18_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MADQLLRKKRRIFIHSVGAGTINALLDCLLEDEVISQEDMNKVRDENDTVMDKARVLIDLVTGKGPKSCCKFIKHLCEEDPQLASKMGLH
PTMs - P57730 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K53 | Acetylation | Uniprot | |
| K64 | Acetylation | Uniprot | |
| K67 | Acetylation | Uniprot |
研究背景
Inhibits generation of IL-1-beta by interacting with caspase-1 and preventing its association with RIP2. Down-regulates the release of IL1B.
Primarily expressed in the heart and placenta.
Interacts with pro-CASP1. Interacts with CARD8.
研究領域
· Organismal Systems > Immune system > NOD-like receptor signaling pathway. (View pathway)
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