製品: K1H1 Antibody
カタログ: DF9002
タンパク質の説明: Rabbit polyclonal antibody to K1H1
アプリケーション: WB IHC
反応性: Human, Mouse, Rat, Monkey
予測: Pig, Bovine
分子量: 47 kDa; 47kD,46kD,49kD(Calculated).
ユニプロット: Q15323 | O76009 | Q14525 | O76011
RRID: AB_2842198

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat,Monkey
予測:
Pig(88%), Bovine(100%)
クローナリティ:
Polyclonal
特異性:
K1H1 Antibody detects endogenous levels of total K1H1.
RRID:
AB_2842198
引用形式: Affinity Biosciences Cat# DF9002, RRID:AB_2842198.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Ha-1; HA1; Hair Keratin acidic hHa1; Hair keratin; hard keratin, type I, 1; hHa1; HKA1; K1H1_HUMAN; K31; keratin 31; Keratin; keratin, hair, acidic,1; keratin, type I cuticular Ha1; Keratin-31; Krt31; KRTHA1; MGC138630; type I cuticular Ha1; type I Ha1; Ha-3I; HA3I; Hair keratin; Hair keratin, type I Ha3-l; Hard keratin, type I,3I; hHa3-I; HHA3-l; HKA3A; K33A; Keratin; Keratin, hair, acidic, 3A; Keratin, type I cuticular Ha3-I; Keratin-33A; Krt1-3; Krt33a; KRTHA3A; KT33A_HUMAN; type I cuticular Ha3-I; type I Ha3-I; HA 3II; HA3II; Hair keratin; Hair keratin type I Ha3 II; Hard keratin type I 3II; hHa3 II; hHa3II; HKA3B; K33B; Keratin 33B; Keratin; Keratin hair acidic 3B; Keratin hair acidic3B; Keratin type I cuticular Ha3 II; Keratin-33B; Keratin33B; KRT 33B; KRT33B; KRTHA 3B; KRTHA3A; KRTHA3B; KT33B_HUMAN; type I cuticular Ha3-II; type I Ha3-II; Type I hair keratin 3B; Ha 4; HA4; Hair keratin; Hair keratin, type I Ha4; Hard keratin type I 4; HHA4; HKA4; K34; Keratin 34; Keratin; Keratin, hair, acidic, 4; Keratin, type I cuticular Ha4; Keratin-34; KRT34; KRT34_HUMAN; KRTHA4; type I cuticular Ha4; type I Ha4;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q15323 K1H1_HUMAN:

Present in scalp but not in hairless skin. Abundantly expressed in the differentiating cortex of growing (anagen) hair. Expression is restricted to the keratinocytes of the hair cortex and is absent from inner root sheath and medulla.

O76009 KT33A_HUMAN:

Expressed in the hair follicles.

O76011 KRT34_HUMAN:

Expressed in the hair follicles.

タンパク質配列:
MPYNFCLPSLSCRTSCSSRPCVPPSCHSCTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDELTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNETRSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCNLPSNPCATTNACSKPIGPCLSNPCTSCVPPAPCTPCAPRPRCGPCNSFVR

MSYSCGLPSLSCRTSCSSRPCVPPSCHGCTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFKTIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNETRSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPSNPCATTNACDKSTGPCISNPCGLRARCGPCNTFGY

MPYNFCLPSLSCRTSCSSRPCVPPSCHGYTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCSKSENARLVVQIDNAKLAADDFRTKYQTEQSLRQLVESDINSLRRILDELTLCRSDLEAQMESLKEELLSLKQNHEQEVNTLRCQLGDRLNVEVDAAPAVDLNQVLNETRNQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRYSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPSNPCATTNACEKPIGSCVTNPCGPRSRCGPCNTFGY

MLYAKPPPTINGIKGLQRKERLKPAHIHLQQLTCFSITCSSTMSYSCCLPSLGCRTSCSSRPCVPPSCHGYTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELEKLIQERSQQQEPLLCPSYQSYFKTIEELQQKILCAKAENARLVVNIDNAKLASDDFRSKYQTEQSLRLLVESDINSIRRILDELTLCKSDLESQVESLREELICLKKNHEEEVNTLRSQLGDRLNVEVDTAPTVDLNQVLNETRSQYEALVEINRREVEQWFATQTEELNKQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEAHYSSQLSQVQSLITNVESQLAEIRCDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPCNPCATTNASGNSCGPCGTSQKGCCN

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Bovine
100
Pig
88
Horse
0
Sheep
0
Dog
0
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q15323/O76009/Q14525/O76011 基板として

Site PTM Type Enzyme
Y70 Phosphorylation
T109 Phosphorylation
Y268 Phosphorylation
T299 Phosphorylation
Site PTM Type Enzyme
Y70 Phosphorylation
T109 Phosphorylation
S157 Phosphorylation
Y268 Phosphorylation
Site PTM Type Enzyme
Y70 Phosphorylation
S92 Phosphorylation
T109 Phosphorylation
K116 Acetylation
K121 Acetylation
T218 Phosphorylation
Y268 Phosphorylation
T299 Phosphorylation
Site PTM Type Enzyme
Y112 Phosphorylation
T151 Phosphorylation
K163 Ubiquitination
S224 Phosphorylation

研究背景

組織特異性:

Present in scalp but not in hairless skin. Abundantly expressed in the differentiating cortex of growing (anagen) hair. Expression is restricted to the keratinocytes of the hair cortex and is absent from inner root sheath and medulla.

タンパク質ファミリー:

Belongs to the intermediate filament family.

組織特異性:

Expressed in the hair follicles.

タンパク質ファミリー:

Belongs to the intermediate filament family.

タンパク質ファミリー:

Belongs to the intermediate filament family.

組織特異性:

Expressed in the hair follicles.

タンパク質ファミリー:

Belongs to the intermediate filament family.

研究領域

· Organismal Systems > Endocrine system > Estrogen signaling pathway.   (View pathway)

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