製品: K2C3 Antibody
カタログ: DF9010
タンパク質の説明: Rabbit polyclonal antibody to K2C3
アプリケーション: WB IHC
反応性: Human, Mouse
予測: Rabbit
分子量: 65 kDa; 64kD(Calculated).
ユニプロット: P12035
RRID: AB_2842206

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
予測:
Rabbit(83%)
クローナリティ:
Polyclonal
特異性:
K2C3 Antibody detects endogenous levels of total K2C3.
RRID:
AB_2842206
引用形式: Affinity Biosciences Cat# DF9010, RRID:AB_2842206.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

65 kDa cytokeratin; CK-3; CK3; Cytokeratin-3; K2C3_HUMAN; K3; Keratin 3; Keratin; Keratin type II cytoskeletal 3; Keratin-3; KRT3; type II cytoskeletal 3; Type-II keratin Kb3;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
P12035 K2C3_HUMAN:

Cornea specific.

タンパク質配列:
MSRQASKTSGGGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFGGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSSISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMDNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLARLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGGSGFGSISGARYGVSGGGFSSASNRGGSIKFSQSSQSSQRYSR

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Rabbit
83
Horse
67
Sheep
67
Pig
0
Bovine
0
Dog
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P12035 基板として

Site PTM Type Enzyme
S13 Phosphorylation
S17 Phosphorylation
S20 Phosphorylation
S56 Phosphorylation
S65 Phosphorylation
K203 Ubiquitination
T204 Phosphorylation
K208 Acetylation
K208 Methylation
K208 Sumoylation
K208 Ubiquitination
S211 Phosphorylation
K215 Acetylation
K215 Ubiquitination
S274 Phosphorylation
K289 Ubiquitination
S364 Phosphorylation
Y393 Phosphorylation
T395 Phosphorylation
T402 Phosphorylation
Y511 Phosphorylation
Y597 Phosphorylation
S605 Phosphorylation
S606 Phosphorylation
S608 Phosphorylation
S613 Phosphorylation

研究背景

組織特異性:

Cornea specific.

サブユニット構造:

Heterotetramer of two type I and two type II keratins. Keratin-3 associates with keratin-12.

タンパク質ファミリー:

Belongs to the intermediate filament family.

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