RAD54B Antibody - #DF9055
| 製品: | RAD54B Antibody |
| カタログ: | DF9055 |
| タンパク質の説明: | Rabbit polyclonal antibody to RAD54B |
| アプリケーション: | WB |
| 反応性: | Human |
| 予測: | Pig, Zebrafish, Bovine, Sheep, Rabbit, Dog |
| 分子量: | 102 kDa; 103kD(Calculated). |
| ユニプロット: | Q9Y620 |
| RRID: | AB_2842251 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF9055, RRID:AB_2842251.
折りたたみ／展開
DNA repair and recombination protein RAD54B; EC 3.6.1.-; Fibrinogen silencer binding protein; FSBP; RAD54 homolog B;
免疫原
Abundantly expressed in testis and spleen. Relatively low levels observed in thymus, prostate, ovary and colon.
- Q9Y620 RA54B_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRRSAAPSQLQGNSFKKPKFIPPGRSNPGLNEEITKLNPDIKLFEGVAINNTFLPSQNDLRICSLNLPSEESTREINNRDNCSGKYCFEAPTLATLDPPHTVHSAPKEVAVSKEQEEKSDSLVKYFSVVWCKPSKKKHKKWEGDAVLIVKGKSFILKNLEGKDIGRGIGYKFKELEKIEEGQTLMICGKEIEVMGVISPDDFSSGRCFQLGGGSTAISHSSQVARKCFSNPFKSVCKPSSKENRQNDFQNCKPRHDPYTPNSLVMPRPDKNHQWVFNKNCFPLVDVVIDPYLVYHLRPHQKEGIIFLYECVMGMRMNGRCGAILADEMGLGKTLQCISLIWTLQCQGPYGGKPVIKKTLIVTPGSLVNNWKKEFQKWLGSERIKIFTVDQDHKVEEFIKSIFYSVLIISYEMLLRSLDQIKNIKFDLLICDEGHRLKNSAIKTTTALISLSCEKRIILTGTPIQNDLQEFFALIDFVNPGILGSLSSYRKIYEEPIILSREPSASEEEKELGERRAAELTCLTGLFILRRTQEIINKYLPPKIENVVFCRPGALQIELYRKLLNSQVVRFCLQGLLENSPHLICIGALKKLCNHPCLLFNSIKEKECSSTCDKNEEKSLYKGLLSVFPADYNPLLFTEKESGKLQVLSKLLAVIHELRPTEKVVLVSNYTQTLNILQEVCKRHGYAYTRLDGQTPISQRQQIVDGFNSQHSSFFIFLLSSKAGGVGLNLIGGSHLILYDIDWNPATDIQAMSRVWRDGQKYPVHIYRLLTTGTIEEKIYQRQISKQGLCGAVVDLTKTSEHIQFSVEELKNLFTLHESSDCVTHDLLDCECTGEEVHTGDSLEKFIVSRDCQLGPHHQKSNSLKPLSMSQLKQWKHFSGDHLNLTDPFLERITENVSFIFQNITTQATGT
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9Y620 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S4 | Phosphorylation | Uniprot | |
| S14 | Phosphorylation | Uniprot | |
| K36 | Ubiquitination | Uniprot | |
| K157 | Ubiquitination | Uniprot | |
| K162 | Ubiquitination | Uniprot | |
| K226 | Methylation | Uniprot | |
| K226 | Ubiquitination | Uniprot | |
| S229 | Phosphorylation | Uniprot | |
| K252 | Ubiquitination | Uniprot | |
| K270 | Ubiquitination | Uniprot | |
| K371 | Ubiquitination | Uniprot | |
| K376 | Ubiquitination | Uniprot | |
| K384 | Ubiquitination | Uniprot | |
| S409 | Phosphorylation | Uniprot | |
| K490 | Ubiquitination | Uniprot | |
| Y492 | Phosphorylation | Uniprot | |
| K590 | Ubiquitination | Uniprot | |
| K603 | Ubiquitination | Uniprot | |
| S608 | Phosphorylation | Uniprot | |
| S609 | Phosphorylation | Uniprot | |
| T610 | Phosphorylation | Uniprot | |
| K621 | Ubiquitination | Uniprot | |
| K639 | Ubiquitination | Uniprot | |
| K643 | Acetylation | Uniprot | |
| K643 | Ubiquitination | Uniprot | |
| S648 | Phosphorylation | Uniprot | |
| Y761 | Phosphorylation | Uniprot | |
| K777 | Ubiquitination | Uniprot | |
| K785 | Ubiquitination | Uniprot | |
| K864 | Ubiquitination | Uniprot | |
| K872 | Ubiquitination | Uniprot | |
| K875 | Ubiquitination | Uniprot |
研究背景
Involved in DNA repair and mitotic recombination. May play an active role in recombination processes in concert with other members of the RAD52 epistasis group.
Nucleus.
Abundantly expressed in testis and spleen. Relatively low levels observed in thymus, prostate, ovary and colon.
Interacts with RAD51 through the NH2-terminal domain. Immunoprecipitation experiments show that the interaction is constitutive and not induced by ionizing radiation. The interaction may be indirect.
Belongs to the SNF2/RAD54 helicase family.
研究領域
· Genetic Information Processing > Replication and repair > Homologous recombination.
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