製品: AGPAT7 Antibody
カタログ: DF9092
タンパク質の説明: Rabbit polyclonal antibody to AGPAT7
アプリケーション: WB
反応性: Human
予測: Rabbit
分子量: 57 kDa; 57kD(Calculated).
ユニプロット: Q643R3
RRID: AB_2842288

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
予測:
Rabbit(88%)
クローナリティ:
Polyclonal
特異性:
AGPAT7 Antibody detects endogenous levels of total AGPAT7.
RRID:
AB_2842288
引用形式: Affinity Biosciences Cat# DF9092, RRID:AB_2842288.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

1 acyl sn glycerol 3 phosphate acyltransferase eta; 1 AGP acyltransferase 7; 1 AGPAT 7; Acyltransferase like 3; AGPAT7; AYTL3; LPAAT eta; Lpcat4; LPEAT2; Lysophosphatidic acid acyltransferase eta; Lysophosphatidylcholine acyltransferase 4;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q643R3 LPCT4_HUMAN:

Widely expressed with predominant level in brain.

タンパク質配列:
MSQGSPGDWAPLDPTPGPPASPNPFVHELHLSRLQRVKFCLLGALLAPIRVLLAFIVLFLLWPFAWLQVAGLSEEQLQEPITGWRKTVCHNGVLGLSRLLFFLLGFLRIRVRGQRASRLQAPVLVAAPHSTFFDPIVLLPCDLPKVVSRAENLSVPVIGALLRFNQAILVSRHDPASRRRVVEEVRRRATSGGKWPQVLFFPEGTCSNKKALLKFKPGAFIAGVPVQPVLIRYPNSLDTTSWAWRGPGVLKVLWLTASQPCSIVDVEFLPVYHPSPEESRDPTLYANNVQRVMAQALGIPATECEFVGSLPVIVVGRLKVALEPQLWELGKVLRKAGLSAGYVDAGAEPGRSRMISQEEFARQLQLSDPQTVAGAFGYFQQDTKGLVDFRDVALALAALDGGRSLEELTRLAFELFAEEQAEGPNRLLYKDGFSTILHLLLGSPHPAATALHAELCQAGSSQGLSLCQFQNFSLHDPLYGKLFSTYLRPPHTSRGTSQTPNASSPGNPTALANGTVQAPKQKGD

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Rabbit
88
Horse
75
Sheep
75
Dog
71
Pig
63
Bovine
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q643R3 基板として

Site PTM Type Enzyme
S2 Phosphorylation
S97 Phosphorylation
K145 Ubiquitination
K216 Ubiquitination
K319 Ubiquitination
K331 Ubiquitination
K335 Ubiquitination
T496 Phosphorylation
S497 Phosphorylation
T499 Phosphorylation
S503 Phosphorylation

研究背景

機能:

Displays acyl-CoA-dependent lysophospholipid acyltransferase activity with a subset of lysophospholipids as substrates; converts lysophosphatidylethanolamine to phosphatidylethanolamine, lysophosphatidylcholine to phosphatidycholine, 1-alkenyl-lysophatidylethanolamine to 1-alkenyl-phosphatidylethanolamine, lysophosphatidylglycerol and alkyl-lysophosphatidylcholine to phosphatidylglycerol and alkyl-phosphatidylcholine, respectively. In contrast, has no lysophosphatidylinositol, glycerol-3-phosphate, diacylglycerol or lysophosphatidic acid acyltransferase activity. Prefers long chain acyl-CoAs (C16, C18) as acyl donors.

細胞の位置付け:

Endoplasmic reticulum membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Widely expressed with predominant level in brain.

タンパク質ファミリー:

Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

研究領域

· Metabolism > Lipid metabolism > Glycerophospholipid metabolism.

· Metabolism > Lipid metabolism > Ether lipid metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

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