製品: ALDH3B2 Antibody
カタログ: DF9188
タンパク質の説明: Rabbit polyclonal antibody to ALDH3B2
アプリケーション: WB IHC IF/ICC
反応性: Human
予測: Zebrafish, Horse, Dog
分子量: 43 kDa; 43kD(Calculated).
ユニプロット: P48448
RRID: AB_2842384

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製品説明

ソース:
Rabbit
アプリケーション:
IHC 1:50-1:200, IF/ICC 1:100-1:500, WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
予測:
Zebrafish(83%), Horse(88%), Dog(100%)
クローナリティ:
Polyclonal
特異性:
ALDH3B2 Antibody detects endogenous levels of total ALDH3B2.
RRID:
AB_2842384
引用形式: Affinity Biosciences Cat# DF9188, RRID:AB_2842384.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Acetaldehyde dehydrogenase 8; AL3B2_HUMAN; Aldehyde dehydrogenase 3 family, member B2; Aldehyde dehydrogenase 8; Aldehyde dehydrogenase family 3 member B2; ALDH3B2; ALDH8; OTTHUMP00000235616;

免疫原

免疫原:
Uniprot:
発現特異性:
P48448 AL3B2_HUMAN:

Salivary gland.

タンパク質配列:
MKDEPRSTNLFMKLDSVFIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEISQGTEKVLAEVLPQYLDQSCFAVVLGGPQETGQLLEHKLDYIFFTGSPRVGKIVMTAATKHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFYGDDPQSSPNLGHIINQKQFQRLRALLGCSRVAIGGQSNESDRYIAPTVLVDVQETEPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERTSSGSFGGNEGFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCLLAPSGLEKLKEIHYPPYTDWNQQLLRWGMGSQSCTLL

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Dog
100
Horse
88
Zebrafish
83
Pig
71
Bovine
71
Sheep
71
Xenopus
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P48448 基板として

Site PTM Type Enzyme
T117 Phosphorylation
T124 Phosphorylation
T127 Phosphorylation
K133 Ubiquitination
K208 Ubiquitination
Y362 Phosphorylation
Y365 Phosphorylation

研究背景

機能:

Oxidizes medium and long chain aldehydes into non-toxic fatty acids.

PTMs:

Geranylgeranylation is important for localization to lipid droplets and enzyme activity.

細胞の位置付け:

Lipid droplet.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Salivary gland.

タンパク質ファミリー:

Belongs to the aldehyde dehydrogenase family.

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