SLC4A3 Antibody - #DF9213
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF9213, RRID:AB_2842409.
折りたたみ／展開
AE 3; AE3; Anion exchange 3; Anion exchange protein 3; Anion exchange protein 3, neuronal; Anion exchanger 3 cardiac isoform; CAE3/BAE3; Cardiac/brain band 3 like protein; Neuronal band 3 like protein; OTTHUMP00000065426; OTTHUMP00000065427; OTTHUMP00000196385; OTTHUMP00000196386; SLC2C; Solute carrier family 4 (anion exchanger) member 3; Solute carrier family 4 member 3; Solute carrier family 4, anion exchanger, member 3;
免疫原
- P48751 B3A3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MANGVIPPPGGASPLPQVRVPLEEPPLSPDVEEEDDDLGKTLAVSRFGDLISKPPAWDPEKPSRSYSERDFEFHRHTSHHTHHPLSARLPPPHKLRRLPPTSARHTRRKRKKEKTSAPPSEGTPPIQEEGGAGVDEEEEEEEEEEGESEAEPVEPPHSGTPQKAKFSIGSDEDDSPGLPGRAAVTKPLPSVGPHTDKSPQHSSSSPSPRARASRLAGEKSRPWSPSASYDLRERLCPGSALGNPGGPEQQVPTDEAEAQMLGSADLDDMKSHRLEDNPGVRRHLVKKPSRTQGGRGSPSGLAPILRRKKKKKKLDRRPHEVFVELNELMLDRSQEPHWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRTIAHGAALLDLEQTTLPGIAHLVVETMIVSDQIRPEDRASVLRTLLLKHSHPNDDKDSGFFPRNPSSSSMNSVLGNHHPTPSHGPDGAVPTMADDLGEPAPLWPHDPDAKEKPLHMPGGDGHRGKSLKLLEKIPEDAEATVVLVGCVPFLEQPAAAFVRLNEAVLLESVLEVPVPVRFLFVMLGPSHTSTDYHELGRSIATLMSDKLFHEAAYQADDRQDLLSAISEFLDGSIVIPPSEVEGRDLLRSVAAFQRELLRKRREREQTKVEMTTRGGYTAPGKELSLELGGSEATPEDDPLLRTGSVFGGLVRDVRRRYPHYPSDLRDALHSQCVAAVLFIYFAALSPAITFGGLLGEKTEGLMGVSELIVSTAVLGVLFSLLGAQPLLVVGFSGPLLVFEEAFFKFCRAQDLEYLTGRVWVGLWLVVFVLALVAAEGSFLVRYISPFTQEIFAFLISLIFIYETFYKLYKVFTEHPLLPFYPPEGALEGSLDAGLEPNGSALPPTEGPPSPRNQPNTALLSLILMLGTFFIAFFLRKFRNSRFLGGKARRIIGDFGIPISILVMVLVDYSITDTYTQKLTVPTGLSVTSPDKRSWFIPPLGSARPFPPWMMVAAAVPALLVLILIFMETQITALIVSQKARRLLKGSGFHLDLLLIGSLGGLCGLFGLPWLTAATVRSVTHVNALTVMRTAIAPGDKPQIQEVREQRVTGVLIASLVGLSIVMGAVLRRIPLAVLFGIFLYMGVTSLSGIQLSQRLLLILMPAKHHPEQPYVTKVKTWRMHLFTCIQLGCIALLWVVKSTAASLAFPFLLLLTVPLRHCLLPRLFQDRELQALDSEDAEPNFDEDGQDEYNELHMPV
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P48751 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S13 | Phosphorylation | Uniprot | |
| S28 | Phosphorylation | Uniprot | |
| S67 | Phosphorylation | Q02156 (PRKCE) | Uniprot |
| S170 | Phosphorylation | Uniprot | |
| T185 | Phosphorylation | Uniprot | |
| T291 | Phosphorylation | Uniprot | |
| S297 | Phosphorylation | Uniprot | |
| K360 | Ubiquitination | Uniprot | |
| S580 | Phosphorylation | Uniprot | |
| T653 | Phosphorylation | Uniprot | |
| Y696 | Phosphorylation | Uniprot | |
| Y716 | Phosphorylation | Uniprot | |
| S721 | Phosphorylation | Uniprot | |
| T725 | Phosphorylation | Uniprot | |
| K922 | Ubiquitination | Uniprot | |
| T955 | Phosphorylation | Uniprot | |
| T958 | Phosphorylation | Uniprot | |
| S961 | Phosphorylation | Uniprot | |
| S969 | Phosphorylation | Uniprot |
研究背景
Plasma membrane anion exchange protein of wide distribution. Mediates at least a part of the Cl(-)/HCO3(-) exchange in cardiac myocytes. Both BAE3 and CAE3 forms transport Cl(-).
Membrane>Multi-pass membrane protein.
Both BAE3 and CAE3 are expressed in failing ventricle.
Belongs to the anion exchanger (TC 2.A.31) family.
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