製品: ABCG4 Antibody
カタログ: DF9252
タンパク質の説明: Rabbit polyclonal antibody to ABCG4
アプリケーション: WB
反応性: Human
予測: Horse, Rabbit, Dog
分子量: 72 kDa; 72kD(Calculated).
ユニプロット: Q9H172
RRID: AB_2842448

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
予測:
Horse(100%), Rabbit(100%), Dog(88%)
クローナリティ:
Polyclonal
特異性:
ABCG4 Antibody detects endogenous levels of total ABCG4.
RRID:
AB_2842448
引用形式: Affinity Biosciences Cat# DF9252, RRID:AB_2842448.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

ABCG 4; ATP binding cassette subfamily G member 4; ATP-binding cassette, sub-family G (WHITE), member 4; Putative ABC transporter; WHITE 2; WHITE2;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q9H172 ABCG4_HUMAN:

Highly expressed in brain tissues with the exception of the spinal cord.

タンパク質配列:
MAEKALEAVGCGLGPGAVAMAVTLEDGAEPPVLTTHLKKVENHITEAQRFSHLPKRSAVDIEFVELSYSVREGPCWRKRGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGMKGQILVNGRPRELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEKQEVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPYLKGLGLHCPTYHNPADFIIEVASGEYGDLNPMLFRAVQNGLCAMAEKKSSPEKNEVPAPCPPCPPEVDPIESHTFATSTLTQFCILFKRTFLSILRDTVLTHLRFMSHVVIGVLIGLLYLHIGDDASKVFNNTGCLFFSMLFLMFAALMPTVLTFPLEMAVFMREHLNYWYSLKAYYLAKTMADVPFQVVCPVVYCSIVYWMTGQPAETSRFLLFSALATATALVAQSLGLLIGAASNSLQVATFVGPVTAIPVLLFSGFFVSFKTIPTYLQWSSYLSYVRYGFEGVILTIYGMERGDLTCLEERCPFREPQSILRALDVEDAKLYMDFLVLGIFFLALRLLAYLVLRYRVKSER

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Rabbit
100
Horse
100
Dog
88
Bovine
75
Sheep
75
Pig
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9H172 基板として

Site PTM Type Enzyme
K82 Ubiquitination
Y567 Phosphorylation
Y570 Phosphorylation
Y573 Phosphorylation
Y583 Phosphorylation

研究背景

機能:

May be involved in macrophage lipid homeostasis.

細胞の位置付け:

Membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Highly expressed in brain tissues with the exception of the spinal cord.

タンパク質ファミリー:

Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.

研究領域

· Environmental Information Processing > Membrane transport > ABC transporters.

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