GCNT4 Antibody - #DF9268
| 製品: | GCNT4 Antibody |
| カタログ: | DF9268 |
| タンパク質の説明: | Rabbit polyclonal antibody to GCNT4 |
| アプリケーション: | WB |
| 反応性: | Human, Mouse |
| 予測: | Pig, Bovine, Horse, Sheep, Dog |
| 分子量: | 53kDa; 53kD(Calculated). |
| ユニプロット: | Q9P109 |
| RRID: | AB_2842464 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF9268, RRID:AB_2842464.
折りたたみ／展開
Core 2 (beta-1,6-N-acetylglucosaminyltransferase); Core 2 branching enzyme 3; Core2 GlcNAc transferase 3; GCNT4; Glucosaminyl (N-acetyl) transferase 4;
免疫原
Predominantly expressed in thymus. Weakly expressed in pancreas, peripheral blood leukocytes, placenta, small intestine and stomach. Barely detectable in liver, spleen, lung and lymph node.
- Q9P109 GCNT4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKIFKCYFKHTLQQKVFILFLTLWLLSLLKLLNVRRLFPQKDIYLVEYSLSTSPFVRNRYTHVKDEVRYEVNCSGIYEQEPLEIGKSLEIRRRDIIDLEDDDVVAMTSDCDIYQTLRGYAQKLVSKEEKSFPIAYSLVVHKDAIMVERLIHAIYNQHNIYCIHYDRKAPDTFKVAMNNLAKCFSNIFIASKLEAVEYAHISRLQADLNCLSDLLKSSIQWKYVINLCGQDFPLKSNFELVSELKKLNGANMLETVKPPNSKLERFTYHHELRRVPYEYVKLPIRTNISKEAPPHNIQIFVGSAYFVLSQAFVKYIFNNSIVQDFFAWSKDTYSPDEHFWATLIRVPGIPGEISRSAQDVSDLQSKTRLVKWNYYEGFFYPSCTGSHLRSVCIYGAAELRWLIKDGHWFANKFDSKVDPILIKCLAEKLEEQQRDWITLPSEKLFMDRNLTTTS
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9P109 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K41 | Acetylation | Uniprot | |
| Y48 | Phosphorylation | Uniprot | |
| Y60 | Phosphorylation | Uniprot | |
| Y135 | Phosphorylation | Uniprot | |
| Y379 | Phosphorylation | Uniprot | |
| S381 | Phosphorylation | Uniprot | |
| T383 | Phosphorylation | Uniprot | |
| S385 | Phosphorylation | Uniprot |
研究背景
Glycosyltransferase that mediates core 2 O-glycan branching, an important step in mucin-type biosynthesis. Does not have core 4 O-glycan or I-branching enzyme activity.
Golgi apparatus membrane>Single-pass type II membrane protein.
Predominantly expressed in thymus. Weakly expressed in pancreas, peripheral blood leukocytes, placenta, small intestine and stomach. Barely detectable in liver, spleen, lung and lymph node.
Belongs to the glycosyltransferase 14 family.
研究領域
· Metabolism > Glycan biosynthesis and metabolism > Mucin type O-glycan biosynthesis.
· Metabolism > Global and overview maps > Metabolic pathways.
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