CEL Antibody - #DF9279
| 製品: | CEL Antibody |
| カタログ: | DF9279 |
| タンパク質の説明: | Rabbit polyclonal antibody to CEL |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse |
| 分子量: | 79 kDa; 79kD(Calculated). |
| ユニプロット: | P19835 |
| RRID: | AB_2842475 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF9279, RRID:AB_2842475.
折りたたみ／展開
BAL; Bile salt-stimulated lipase; BSDL; BSSL; Bucelipase; Carboxyl ester lipase (bile salt stimulated lipase); Carboxyl ester lipase; CEase; CEL; CELL; Cholesterol esterase; FAP; FAPP; Fetoacinar pancreatic protein; LIPA; Lysophospholipase, pancreatic; MODY8; Pancreatic lysophospholipase; Sterol esterase;
免疫原
Mammary gland and pancreas. Detected in pancreatic and duodenal juice (at protein level) (PubMed:21784842). Expressed by eosinophils.
- P19835 CEL_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGRLQLVVLGLTCCWAVASAAKLGAVYTEGGFVEGVNKKLGLLGDSVDIFKGIPFAAPTKALENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYANAADIDYIAGTNNMDGHIFASIDMPAINKGNKKVTEEDFYKLVSEFTITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMPVYPKWVGADHADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKMGSSSMKRSLRTNFLRYWTLTYLALPTVTDQEATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPPTDDSKEAQMPAVIRF
PTMs - P19835 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y27 | Phosphorylation | Uniprot | |
| T28 | Phosphorylation | Uniprot | |
| S238 | Phosphorylation | Uniprot | |
| S245 | Phosphorylation | Uniprot | |
| Y365 | Phosphorylation | Uniprot | |
| T494 | Phosphorylation | Uniprot | |
| T558 | O-Glycosylation | Uniprot | |
| T569 | O-Glycosylation | Uniprot | |
| T579 | O-Glycosylation | Uniprot | |
| T607 | O-Glycosylation | Uniprot | |
| T618 | O-Glycosylation | Uniprot | |
| T629 | O-Glycosylation | Uniprot | |
| T640 | O-Glycosylation | Uniprot | |
| T651 | O-Glycosylation | Uniprot | |
| T662 | O-Glycosylation | Uniprot | |
| T673 | O-Glycosylation | Uniprot |
研究背景
Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs). Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs (By similarity). Has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins.
N- and O-glycosylated.
Secreted.
Mammary gland and pancreas. Detected in pancreatic and duodenal juice (at protein level). Expressed by eosinophils.
Interacts with CLC.
Belongs to the type-B carboxylesterase/lipase family.
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