製品: CHERP Antibody
カタログ: DF9296
タンパク質の説明: Rabbit polyclonal antibody to CHERP
アプリケーション: WB
反応性: Human, Mouse
予測: Pig, Bovine, Horse, Sheep, Dog, Chicken, Xenopus
分子量: 104 kDa; 104kD(Calculated).
ユニプロット: Q8IWX8
RRID: AB_2842492

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
予測:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Dog(100%), Chicken(80%), Xenopus(80%)
クローナリティ:
Polyclonal
特異性:
CHERP Antibody detects endogenous levels of total CHERP.
RRID:
AB_2842492
引用形式: Affinity Biosciences Cat# DF9296, RRID:AB_2842492.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Calcium homeostasis endoplasmic reticulum protein; DAN16; DAN26; ERPROT 213 21; ERPROT21321; Protein with polyglutamine repeat; SCAF6; SR related CTD associated factor 6; SRA1;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q8IWX8 CHERP_HUMAN:

Expressed in brain, placenta, lung, liver, kidney, pancreas, cardiac and skeletal muscle, and in cultured HEL and Dami cells.

タンパク質配列:
MEMPLPPDDQELRNVIDKLAQFVARNGPEFEKMTMEKQKDNPKFSFLFGGEFYSYYKCKLALEQQQLICKQQTPELEPAATMPPLPQPPLAPAAPIPPAQGAPSMDELIQQSQWNLQQQEQHLLALRQEQVTAAVAHAVEQQMQKLLEETQLDMNEFDNLLQPIIDTCTKDAISAGKNWMFSNAKSPPHCELMAGHLRNRITADGAHFELRLHLIYLINDVLHHCQRKQARELLAALQKVVVPIYCTSFLAVEEDKQQKIARLLQLWEKNGYFDDSIIQQLQSPALGLGQYQATLINEYSSVVQPVQLAFQQQIQTLKTQHEEFVTSLAQQQQQQQQQQQQLQMPQMEAEVKATPPPPAPPPAPAPAPAIPPTTQPDDSKPPIQMPGSSEYEAPGGVQDPAAAGPRGPGPHDQIPPNKPPWFDQPHPVAPWGQQQPPEQPPYPHHQGGPPHCPPWNNSHEGMWGEQRGDPGWNGQRDAPWNNQPDAAWNSQFEGPWNSQHEQPPWGGGQREPPFRMQRPPHFRGPFPPHQQHPQFNQPPHPHNFNRFPPRFMQDDFPPRHPFERPPYPHRFDYPQGDFPAEMGPPHHHPGHRMPHPGINEHPPWAGPQHPDFGPPPHGFNGQPPHMRRQGPPHINHDDPSLVPNVPYFDLPAGLMAPLVKLEDHEYKPLDPKDIRLPPPMPPSERLLAAVEAFYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNSAPPIPDSRLGEENKGHQMLVKMGWSGSGGLGAKEQGIQDPIKGGDVRDKWDQYKGVGVALDDPYENYRRNKSYSFIARMKARDECK

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Xenopus
80
Chicken
80
Zebrafish
63
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q8IWX8 基板として

Site PTM Type Enzyme
M1 Acetylation
K18 Acetylation
K18 Ubiquitination
K177 Ubiquitination
S186 Phosphorylation
K239 Acetylation
R510 Methylation
R546 Methylation
R675 Methylation
S683 Phosphorylation
Y694 Phosphorylation
S695 Phosphorylation
S698 Phosphorylation
S705 Phosphorylation
Y714 Phosphorylation
S750 Phosphorylation
S755 Phosphorylation
S763 Phosphorylation
S765 Phosphorylation
S767 Phosphorylation
S773 Phosphorylation
S775 Phosphorylation
S777 Phosphorylation
S779 Phosphorylation
S785 Phosphorylation
S789 Phosphorylation
S792 Phosphorylation
S798 Phosphorylation
S800 Phosphorylation
S804 Phosphorylation
Y805 Phosphorylation
S806 Phosphorylation
R811 Methylation
S813 Phosphorylation
S815 Phosphorylation
S817 Phosphorylation
T819 Phosphorylation
S822 Phosphorylation
S823 Phosphorylation
S828 Phosphorylation
S830 Phosphorylation
S837 Phosphorylation
R838 Methylation
K844 Sumoylation
S855 Phosphorylation
S857 Phosphorylation
K879 Acetylation
K879 Ubiquitination
Y883 Phosphorylation
K884 Ubiquitination
Y894 Phosphorylation
Y897 Phosphorylation
K901 Acetylation
K901 Methylation
K901 Ubiquitination
S902 Phosphorylation
Y903 Phosphorylation
S904 Phosphorylation
R908 Methylation

研究背景

機能:

Involved in calcium homeostasis, growth and proliferation.

細胞の位置付け:

Cytoplasm. Cytoplasm>Perinuclear region. Endoplasmic reticulum.
Note: Distributed throughout the cytoplasm and also localizes to the perinuclear region of both human erythroleukemia (HEL) cells and Jurkat cells. Colocalizes with ITPR1.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in brain, placenta, lung, liver, kidney, pancreas, cardiac and skeletal muscle, and in cultured HEL and Dami cells.

研究領域

· Genetic Information Processing > Transcription > Spliceosome.

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