PDE1A Antibody - #DF9298
| 製品: | PDE1A Antibody |
| カタログ: | DF9298 |
| タンパク質の説明: | Rabbit polyclonal antibody to PDE1A |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 61 kDa; 61kD(Calculated). |
| ユニプロット: | P54750 |
| RRID: | AB_2842494 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF9298, RRID:AB_2842494.
折りたたみ／展開
3' 5' cyclic nucleotide phosphodiesterase; 5''-cyclic nucleotide phosphodiesterase 1A; 61 kDa Cam PDE; 61 kDa Cam-PDE; Calcium/calmodulin dependent 3' 5' cyclic nucleotide phosphodiesterase 1A; Calcium/Calmodulin stimulated cyclic nucleotide phosphodiesterase; Calcium/calmodulin-dependent 3''; Calmodulin-dependent Phosphodiesterase; Cam PDE 1A; Cam-PDE 1A; CAM-PDE-1A; HCAM 1; hCam-1; HCAM1; HSPDE1A; MGC26303; PDE 1A; PDE1A; PDE1A_HUMAN; Phosphodiesterase 1A; Phosphodiesterase 1A calmodulin dependent;
免疫原
- P54750 PDE1A_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGSSATEIEELENTTFKYLTGEQTEKMWQRLKGILRCLVKQLERGDVNVVDLKKNIEYAASVLEAVYIDETRRLLDTEDELSDIQTDSVPSEVRDWLASTFTRKMGMTKKKPEEKPKFRSIVHAVQAGIFVERMYRKTYHMVGLAYPAAVIVTLKDVDKWSFDVFALNEASGEHSLKFMIYELFTRYDLINRFKIPVSCLITFAEALEVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGIMHWLTELEILAMVFAAAIHDYEHTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLMQEEEMNILINLSKDDWRDLRNLVIEMVLSTDMSGHFQQIKNIRNSLQQPEGIDRAKTMSLILHAADISHPAKSWKLHYRWTMALMEEFFLQGDKEAELGLPFSPLCDRKSTMVAQSQIGFIDFIVEPTFSLLTDSTEKIVIPLIEEASKAETSSYVASSSTTIVGLHIADALRRSNTKGSMSDGSYSPDYSLAAVDLKSFKNNLVDIIQQNKERWKELAAQEARTSSQKCEFIHQ
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P54750 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K53 | Ubiquitination | Uniprot | |
| Y58 | Phosphorylation | Uniprot | |
| T71 | Phosphorylation | Uniprot | |
| S82 | Phosphorylation | Uniprot | |
| T86 | Phosphorylation | Uniprot | |
| T185 | Phosphorylation | Uniprot | |
| S198 | Phosphorylation | Uniprot | |
| T202 | Phosphorylation | Uniprot | |
| S212 | Phosphorylation | Uniprot | |
| Y214 | Phosphorylation | Uniprot | |
| Y282 | Phosphorylation | Uniprot | |
| S403 | Phosphorylation | Uniprot | |
| S416 | Phosphorylation | Uniprot | |
| S487 | Phosphorylation | Uniprot |
研究背景
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher affinity for cGMP than for cAMP.
Several tissues, including brain, kidney, testes and heart.
Homodimer. Interacts with YWHAZ.
Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
研究領域
· Environmental Information Processing > Signal transduction > Calcium signaling pathway. (View pathway)
· Human Diseases > Substance dependence > Morphine addiction.
· Metabolism > Nucleotide metabolism > Purine metabolism.
· Organismal Systems > Sensory system > Olfactory transduction.
· Organismal Systems > Sensory system > Taste transduction.
· Organismal Systems > Endocrine system > Renin secretion.
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