Cytokeratin 5 Antibody - #AF0194
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF0194, RRID:AB_2833387.
折りたたみ/展開
58 kDa cytokeratin; CK-5; CK5; Cytokeratin-5; Cytokeratin5; DDD; DDD1; EBS2; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; K2C5_HUMAN; K5; keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); Keratin 5; Keratin; keratin complex 2, basic, gene 5; keratin, type II cytoskeletal 5; Keratin-5; Keratin5; KRT 5; Krt5; KRT5A; type II cytoskeletal 5; Type-II keratin Kb5;
免疫原
- P13647 K2C5_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSRQSSVSFRSGGSRSFSTASAITPSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGYGSRSLYNLGGSKRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGGGAGFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDEINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAESWYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQRGELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEECRLSGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGSSGSYYSSSSGGVGLGGGLSVGGSGFSASSGRGLGVGFGSGGGSSSSVKFVSTTSSSRKSFKS
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P13647 基板として
Site | PTM Type | Enzyme | Source |
---|---|---|---|
S2 | Phosphorylation | Uniprot | |
S5 | Phosphorylation | Uniprot | |
S8 | Phosphorylation | Uniprot | |
S11 | Phosphorylation | Uniprot | |
S14 | Phosphorylation | Uniprot | |
S16 | Phosphorylation | Uniprot | |
S18 | Phosphorylation | Uniprot | |
T19 | Phosphorylation | Uniprot | |
S21 | Phosphorylation | Uniprot | |
T24 | Phosphorylation | Uniprot | |
S26 | Phosphorylation | Uniprot | |
S28 | Phosphorylation | Uniprot | |
S31 | Phosphorylation | Uniprot | |
S36 | Phosphorylation | Uniprot | |
S38 | Phosphorylation | Uniprot | |
S50 | Phosphorylation | Uniprot | |
Y60 | Phosphorylation | Uniprot | |
S62 | Phosphorylation | Uniprot | |
S64 | Phosphorylation | Uniprot | |
Y66 | Phosphorylation | Uniprot | |
S71 | Phosphorylation | Uniprot | |
K72 | Acetylation | Uniprot | |
K72 | Methylation | Uniprot | |
S75 | Phosphorylation | Uniprot | |
S77 | Phosphorylation | Uniprot | |
T78 | Phosphorylation | Uniprot | |
S82 | Phosphorylation | Uniprot | |
T151 | Phosphorylation | Uniprot | |
K173 | Ubiquitination | Uniprot | |
T174 | Phosphorylation | Uniprot | |
K178 | Acetylation | Uniprot | |
K178 | Methylation | Uniprot | |
K178 | Sumoylation | Uniprot | |
K178 | Ubiquitination | Uniprot | |
S181 | Phosphorylation | Uniprot | |
K185 | Acetylation | Uniprot | |
K185 | Ubiquitination | Uniprot | |
K199 | Methylation | Uniprot | |
Y222 | Phosphorylation | Uniprot | |
S242 | Phosphorylation | Uniprot | |
K257 | Methylation | Uniprot | |
K257 | Ubiquitination | Uniprot | |
Y258 | Phosphorylation | Uniprot | |
K264 | Methylation | Uniprot | |
K264 | Ubiquitination | Uniprot | |
Y283 | Phosphorylation | Uniprot | |
S337 | Phosphorylation | Uniprot | |
Y346 | Phosphorylation | Uniprot | |
S353 | Phosphorylation | Uniprot | |
T355 | Phosphorylation | Uniprot | |
S359 | Phosphorylation | Uniprot | |
Y361 | Phosphorylation | Uniprot | |
T363 | Phosphorylation | Uniprot | |
Y365 | Phosphorylation | Uniprot | |
K426 | Ubiquitination | Uniprot | |
K443 | Sumoylation | Uniprot | |
Y453 | Phosphorylation | Uniprot | |
R480 | Methylation | Uniprot | |
S567 | Phosphorylation | Uniprot | |
S571 | Phosphorylation | Uniprot | |
S574 | Phosphorylation | Uniprot | |
S579 | Phosphorylation | Uniprot | |
S587 | Phosphorylation | Uniprot | |
S590 | Phosphorylation | Uniprot |
研究背景
Heterodimer of a type I and a type II keratin. Heterodimer with type I keratin KRT25 leading to the formation of keratin intermediate filament (KIF) network. Heterodimer with KRT14. Interacts with TCHP. Interacts with EPPK1 (By similarity).
Belongs to the intermediate filament family.
参考文献
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