製品: CKLF Antibody
カタログ: DF9374
タンパク質の説明: Rabbit polyclonal antibody to CKLF
アプリケーション: WB IHC
反応性: Human, Mouse, Rat
予測: Horse
分子量: 17 kDa; 17kD(Calculated).
ユニプロット: Q9UBR5
RRID: AB_2842570

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Horse(83%)
クローナリティ:
Polyclonal
特異性:
CKLF Antibody detects endogenous levels of total CKLF.
RRID:
AB_2842570
引用形式: Affinity Biosciences Cat# DF9374, RRID:AB_2842570.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

C32; Chemokine-like factor; chemokine-like factor 1; chemokine-like factor 2; chemokine-like factor 3; chemokine-like factor 4; CKLF1; CKLF2; CKLF3; CKLF4; CKLFSF2; HSPC224; transmembrane proteolipid; UCK-1; UCK1;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q9UBR5 CKLF_HUMAN:

Isoform 1, isoform 2, isoform 3 and isoform 4 have highest expression levels in adult spleen, lung, testis, ovary, peripheral blood leukocyte, placenta, pancreas, and in fetal brain, skeletal muscle, thymus and heart. Lower expression levels in adult skeletal muscle, liver, thymus colon, prostate and fetal spleen and liver.

タンパク質配列:
MDNVQPKIKHRPFCFSVKGHVKMLRLALTVTSMTFFIIAQAPEPYIVITGFEVTVILFFILLYVLRLDRLMKWLFWPLLDIINSLVTTVFMLIVSVLALIPETTTLTVGGGVFALVTAVCCLADGALIYRKLLFNPSGPYQKKPVHEKKEVL

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Horse
83
Pig
75
Dog
75
Bovine
67
Sheep
67
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9UBR5 基板として

Site PTM Type Enzyme
K7 Ubiquitination
K9 Ubiquitination
K18 Methylation
K22 Methylation
K131 Ubiquitination
S137 Phosphorylation
Y140 Phosphorylation

研究背景

機能:

May play an important role in inflammation and regeneration of skeletal muscle. Partly inhibited by interleukin 10.

has chemotactic response in monocytes, neutrophils and lymphocytes. Binds CCR4.

細胞の位置付け:

Secreted.

Membrane>Multi-pass membrane protein.

Membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Isoform 1, isoform 2, isoform 3 and isoform 4 have highest expression levels in adult spleen, lung, testis, ovary, peripheral blood leukocyte, placenta, pancreas, and in fetal brain, skeletal muscle, thymus and heart. Lower expression levels in adult skeletal muscle, liver, thymus colon, prostate and fetal spleen and liver.

タンパク質ファミリー:

Belongs to the chemokine-like factor family.

Restrictive clause

 

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