CHSY3 Antibody - #DF9378
| 製品: | CHSY3 Antibody |
| カタログ: | DF9378 |
| タンパク質の説明: | Rabbit polyclonal antibody to CHSY3 |
| アプリケーション: | WB |
| 反応性: | Human, Mouse, Rat |
| 予測: | Bovine, Dog |
| 分子量: | 100 kDa; 100kD(Calculated). |
| ユニプロット: | Q70JA7 |
| RRID: | AB_2842574 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF9378, RRID:AB_2842574.
折りたたみ／展開
Carbohydrate synthase 2; Chondroitin glucuronyltransferase 3; Chondroitin sulfate synthase 3; Chondroitin synthase 2; CHSS3_HUMAN; ChSy-2; CHSY2; Chsy3; CSS3; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 3; N-acetylgalactosaminyltransferase 3;
免疫原
- Q70JA7 CHSS3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAVRSRRPWMSVALGLVLGFTAASWLIAPRVAELSERKRRGSSLCSYYGRSAAGPRAGAQQPLPQPQSRPRQEQSPPPARQDLQGPPLPEAAPGITSFRSSPWQQPPPLQQRRRGREPEGATGLPGAPAAEGEPEEEDGGAAGQRRDGRPGSSHNGSGDGGAAAPSARPRDFLYVGVMTAQKYLGSRALAAQRTWARFIPGRVEFFSSQQPPNAGQPPPPLPVIALPGVDDSYPPQKKSFMMIKYMHDHYLDKYEWFMRADDDVYIKGDKLEEFLRSLNSSKPLYLGQTGLGNIEELGKLGLEPGENFCMGGPGMIFSREVLRRMVPHIGECLREMYTTHEDVEVGRCVRRFGGTQCVWSYEMQQLFHENYEHNRKGYIQDLHNSKIHAAITLHPNKRPAYQYRLHNYMLSRKISELRYRTIQLHRESALMSKLSNTEVSKEDQQLGVIPSFNHFQPRERNEVIEWEFLTGKLLYSAAENQPPRQSLSSILRTALDDTVLQVMEMINENAKSRGRLIDFKEIQYGYRRVNPMHGVEYILDLLLLYKRHKGRKLTVPVRRHAYLQQLFSKPFFRETEELDVNSLVESINSETQSFSFISNSLKILSSFQGAKEMGGHNEKKVHILVPLIGRYDIFLRFMENFENMCLIPKQNVKLVIILFSRDSGQDSSKHIELIKGYQNKYPKAEMTLIPMKGEFSRGLGLEMASAQFDNDTLLLFCDVDLIFREDFLQRCRDNTIQGQQVYYPIIFSQYDPKVTNGGNPPTDDYFIFSKKTGFWRDYGYGITCIYKSDLLGAGGFDTSIQGWGLEDVDLYNKVILSGLRPFRSQEVGVVHIFHPVHCDPNLDPKQYKMCLGSKASTFASTMQLAELWLEKHLGVRYNRTLS
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q70JA7 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T96 | Phosphorylation | Uniprot | |
| S97 | Phosphorylation | Uniprot | |
| S100 | O-Glycosylation | Uniprot | |
| S101 | O-Glycosylation | Uniprot | |
| S411 | Phosphorylation | Uniprot | |
| Y526 | Phosphorylation | Uniprot | |
| T687 | Phosphorylation | Uniprot | |
| S860 | Phosphorylation | Uniprot |
研究背景
Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Specific activity is much reduced compared to CHSY1.
Golgi apparatus>Golgi stack membrane>Single-pass type II membrane protein.
Detected at low levels in brain, cerebral cortex, uterus and small intestine.
Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
研究領域
· Metabolism > Glycan biosynthesis and metabolism > Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate.
· Metabolism > Global and overview maps > Metabolic pathways.
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