CMTM5 Antibody - #DF9387

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製品: CMTM5 Antibody
カタログ: DF9387
タンパク質の説明: Rabbit polyclonal antibody to CMTM5
アプリケーション: WB
反応性: Human, Rat
分子量: 25 kDa; 25kD(Calculated).
ユニプロット: Q96DZ9
RRID: AB_2842583

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Rat
クローナリティ:
Polyclonal
特異性:
CMTM5 Antibody detects endogenous levels of total CMTM5.
RRID:
AB_2842583
引用形式: Affinity Biosciences Cat# DF9387, RRID:AB_2842583.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

1500005P16Rik; 2900052H21Rik; Chemokine like factor super family 5; Chemokine like factor super family five variant 4; Chemokine like factor superfamily 5; Chemokine-like factor superfamily member 5; CKLF-like MARVEL transmembrane domain containing 5; CKLF-like MARVEL transmembrane domain-containing protein 5; CKLF5_HUMAN; CKLFSF5; CMTM5; FLJ37521;

免疫原

免疫原:
Uniprot:

Q96DZ9(CKLF5_HUMAN) >>Visit HPA database.

遺伝子(ID):
CMTM5(116173)
発現特異性:
Q96DZ9 CKLF5_HUMAN:

Highly expressed in the brain.

タンパク質配列:
MLSARDRRDRHPEEGVVAELQGFAVDKAFLTSHKGILLETELALTLIIFICFTASISAYMAAALLEFFITLAFLFLYATQYYQRFDRINWPCLLQGHGQSGGPHPLDLLSHSAKVQPQPWPGLTPPGWHTPAAVPWVPAPAPGFWSWLLWFICFHSLGSSDFLRCVSAIIIFLVVSFAAVTSRDGAAIAAFVFGIILVSIFAYDAFKIYRTEMAPGASQGDQQ

研究背景

細胞の位置付け:

Membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Highly expressed in the brain.

タンパク質ファミリー:

Belongs to the chemokine-like factor family.

参考文献

1). Expressions of ZNF436, β-catenin, EGFR, and CMTM5 in breast cancer and their clinical significances. EUROPEAN JOURNAL OF HISTOCHEMISTRY, 2021 (PubMed: 33478201) [IF=2.0]

Application: IHC    Species: Human    Sample: breast cancer and paracancerous tissues

Figure 1.Expression levels of ZNF436, β-catenin, EGFR and CMTM5 in breast cancer and paracancerous tissues. The expression levels of ZNF436, β-catenin and EGFR in breast cancer tissues were significantly higher than those in adjacent tissues (p<0.05); CMTM5 was highly expressed in adjacent tissues (p<0.05).

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