RPC9 Antibody - #DF9462
| 製品: | RPC9 Antibody |
| カタログ: | DF9462 |
| タンパク質の説明: | Rabbit polyclonal antibody to RPC9 |
| アプリケーション: | WB |
| 反応性: | Human |
| 予測: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 17 kDa; 17kD(Calculated). |
| ユニプロット: | O75575 |
| RRID: | AB_2842658 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF9462, RRID:AB_2842658.
折りたたみ／展開
Calcitonin gene related peptide receptor component; Calcitonin gene related peptide receptor component protein; Calcitonin gene-related peptide-receptor component protein; CGRP receptor component protein; CGRP-RCP; CGRP-receptor component protein; CGRPRCP; CRCP; DNA-directed RNA polymerase III subunit RPC9; HsC17; RCP; RCP9; RNA polymerase III subunit C9; RPC9_HUMAN;
免疫原
- O75575 RPC9_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEVKDANSALLSNYEVFQLLTDLKEQRKESGKNKHSSGQQNLNTITYETLKYISKTPCRHQSPEIVREFLTALKSHKLTKAEKLQLLNHRPVTAVEIQLMVEESEERLTEEQIEALLHTVTSILPAEPEAEQKKNTNSNVAMDEEDPA
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O75575 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K24 | Ubiquitination | Uniprot | |
| K34 | Ubiquitination | Uniprot | |
| S37 | Phosphorylation | Uniprot | |
| T46 | Phosphorylation | Uniprot | |
| Y47 | Phosphorylation | Uniprot | |
| K51 | Acetylation | Uniprot | |
| K55 | Ubiquitination | Uniprot | |
| T56 | Phosphorylation | Uniprot | |
| S62 | Phosphorylation | Uniprot | |
| K74 | Ubiquitination | Uniprot | |
| K134 | Ubiquitination | Uniprot |
研究背景
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).
Accessory protein for the calcitonin gene-related peptide (CGRP) receptor. It modulates CGRP responsiveness in a variety of tissues.
Nucleus. Cell membrane>Peripheral membrane protein>Cytoplasmic side.
Ubiquitous. Most prevalent in testis.
Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits (By similarity). Interacts with POLR3H/RPC8. POLR3H/RPC8 and CRCP/RPC9 probably form a Pol III subcomplex.
Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
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