DNAL4 Antibody - #DF9470

(3)  
製品: DNAL4 Antibody
カタログ: DF9470
タンパク質の説明: Rabbit polyclonal antibody to DNAL4
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse
予測: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
分子量: 12 kDa; 12kD(Calculated).
ユニプロット: O96015
RRID: AB_2842666

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関連ダウンロード
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
IF/ICC 1:100-1:500, WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
予測:
Pig(100%), Bovine(100%), Horse(88%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(100%)
クローナリティ:
Polyclonal
特異性:
DNAL4 Antibody detects endogenous levels of total DNAL4.
RRID:
AB_2842666
引用形式: Affinity Biosciences Cat# DF9470, RRID:AB_2842666.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

D15Ertd424e; Dnal4; DNAL4_HUMAN; Dnalc4; Dynein axonemal light chain 4; Dynein light chain 4, axonemal; Dynein light chain, outer arm 4; Dynein, axonemal, light 4; Dynein, axonemal, light polypeptide 4; MGC105573; PIG27; Proliferation inducing gene 27; Proliferation inducing protein 27;

免疫原

免疫原:
Uniprot:

O96015(DNAL4_HUMAN) >>Visit HPA database.

遺伝子(ID):
DNAL4(10126)
タンパク質配列:
MGETEGKKDEADYKRLQTFPLVRHSDMPEEMRVETMELCVTACEKFSNNNESAAKMIKETMDKKFGSSWHVVIGEGFGFEITHEVKNLLYLYFGGTLAVCVWKCS

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Sheep
100
Dog
100
Xenopus
100
Chicken
100
Rabbit
100
Horse
88
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O96015 基板として

Site PTM Type Enzyme
K55 Ubiquitination

研究背景

機能:

Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity (By similarity).

細胞の位置付け:

Cytoplasm>Cytoskeleton>Cilium axoneme.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Consists of at least two heavy chains and a number of intermediate and light chains.

タンパク質ファミリー:

Belongs to the dynein light chain family.

研究領域

· Human Diseases > Neurodegenerative diseases > Huntington's disease.

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