製品: FUT2 Antibody
カタログ: DF9523
タンパク質の説明: Rabbit polyclonal antibody to FUT2
アプリケーション: WB
反応性: Human, Rat
予測: Pig, Bovine, Rabbit, Dog, Xenopus
分子量: 39 kDa; 39kD(Calculated).
ユニプロット: Q10981
RRID: AB_2842719

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Rat
予測:
Pig(100%), Bovine(100%), Rabbit(92%), Dog(92%), Xenopus(82%)
クローナリティ:
Polyclonal
特異性:
FUT2 Antibody detects endogenous levels of total FUT2.
RRID:
AB_2842719
引用形式: Affinity Biosciences Cat# DF9523, RRID:AB_2842719.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

2)FT 2; Alpha (1,2) fucosyltransferase; Alpha(1; Alpha(1,2)FT 2; Alpha(1,2)FT2; B12QTL1; fucosyltransferase 2 (secretor status included); Fucosyltransferase 2; FUT2; FUT2_HUMAN; Galactoside 2-alpha-L-fucosyltransferase 2; GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 2; SE; SE2; SEC2; Secretor blood group alpha-2-fucosyltransferase; Secretor factor; Sej;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q10981 FUT2_HUMAN:

Small intestine, colon and lung.

タンパク質配列:
MLVVQMPFSFPMAHFILFVFTVSTIFHVQQRLAKIQAMWELPVQIPVLASTSKALGPSQLRGMWTINAIGRLGNQMGEYATLYALAKMNGRPAFIPAQMHSTLAPIFRITLPVLHSATASRIPWQNYHLNDWMEEEYRHIPGEYVRFTGYPCSWTFYHHLRQEILQEFTLHDHVREEAQKFLRGLQVNGSRPGTFVGVHVRRGDYVHVMPKVWKGVVADRRYLQQALDWFRARYSSLIFVVTSNGMAWCRENIDTSHGDVVFAGDGIEGSPAKDFALLTQCNHTIMTIGTFGIWAAYLTGGDTIYLANYTLPDSPFLKIFKPEAAFLPEWTGIAADLSPLLKH

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Dog
92
Rabbit
92
Xenopus
82
Horse
0
Sheep
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q10981 基板として

Site PTM Type Enzyme
Y205 Phosphorylation

研究背景

機能:

Mediates the transfer of fucose to the terminal galactose on glycan chains of cell surface glycoproteins and glycolipids. The resulting epitope plays a role in cell-cell interaction including host-microbe interaction. Mediates interaction with intestinal microbiota influencing its composition. Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble ABO blood group antigen synthesis pathway.

細胞の位置付け:

Golgi apparatus>Golgi stack membrane>Single-pass type II membrane protein.
Note: Membrane-bound form in trans cisternae of Golgi.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Small intestine, colon and lung.

タンパク質ファミリー:

Belongs to the glycosyltransferase 11 family.

研究領域

· Metabolism > Glycan biosynthesis and metabolism > Glycosphingolipid biosynthesis - lacto and neolacto series.

· Metabolism > Glycan biosynthesis and metabolism > Glycosphingolipid biosynthesis - globo and isoglobo series.

· Metabolism > Global and overview maps > Metabolic pathways.

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