TUBGCP2 Antibody - #DF9527
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF9527, RRID:AB_2842723.
折りたたみ／展開
1700022B05Rik; A disintegrin and metalloprotease domain 8; Adam8; Gamma ring complex protein 103 kDa; Gamma tubulin complex component 2; Gamma tubulin complex protein 2; Gamma-ring complex protein 103 kDa; Gamma-tubulin complex component 2; GCP 2; GCP-2; GCP2; GCP2_HUMAN; h103p; hGCP2; hGrip103; hSpc97; MGC138162; MGC83533; OTTHUMP00000020808; SPBC97; Spc97p; Spindle pole body protein Spc97 homolog; TUBGCP 2; Tubgcp2; Tubulin gamma complex associated protein 2;
免疫原
- Q9BSJ2 GCP2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSEFRIHHDVNELLSLLRVHGGDGAEVYIDLLQKNRTPYVTTTVSAHSAKVKIAEFSRTPEDFLKKYDELKSKNTRNLDPLVYLLSKLTEDKETLQYLQQNAKERAELAAAAVGSSTTSINVPAAASKISMQELEELRKQLGSVATGSTLQQSLELKRKMLRDKQNKKNSGQHLPIFPAWVYERPALIGDFLIGAGISTDTALPIGTLPLASQESAVVEDLLYVLVGVDGRYVSAQPLAGRQSRTFLVDPNLDLSIRELVHRILPVAASYSAVTRFIEEKSSFEYGQVNHALAAAMRTLVKEHLILVSQLEQLHRQGLLSLQKLWFYIQPAMRTMDILASLATSVDKGECLGGSTLSLLHDRSFSYTGDSQAQELCLYLTKAASAPYFEVLEKWIYRGIIHDPYSEFMVEEHELRKERIQEDYNDKYWDQRYTIVQQQIPSFLQKMADKILSTGKYLNVVRECGHDVTCPVAKEIIYTLKERAYVEQIEKAFNYASKVLLDFLMEEKELVAHLRSIKRYFLMDQGDFFVHFMDLAEEELRKPVEDITPPRLEALLELALRMSTANTDPFKDDLKIDLMPHDLITQLLRVLAIETKQEKAMAHADPTELALSGLEAFSFDYIVKWPLSLIINRKALTRYQMLFRHMFYCKHVERQLCSVWISNKTAKQHSLHSAQWFAGAFTLRQRMLNFVQNIQYYMMFEVMEPTWHILEKNLKSASNIDDVLGHHTGFLDTCLKDCMLTNPELLKVFSKLMSVCVMFTNCMQKFTQSMKLDGELGGQTLEHSTVLGLPAGAEERARKELARKHLAEHADTVQLVSGFEATINKFDKNFSAHLLDLLARLSIYSTSDCEHGMASVISRLDFNGFYTERLERLSAERSQKATPQVPVLRGPPAPAPRVAVTAQ
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9BSJ2 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T37 | Phosphorylation | Uniprot | |
| Y39 | Phosphorylation | Uniprot | |
| K65 | Ubiquitination | Uniprot | |
| Y83 | Phosphorylation | Uniprot | |
| S86 | Phosphorylation | Uniprot | |
| K92 | Ubiquitination | Uniprot | |
| K103 | Ubiquitination | Uniprot | |
| K157 | Ubiquitination | Uniprot | |
| K426 | Ubiquitination | Uniprot | |
| K449 | Ubiquitination | Uniprot | |
| K455 | Ubiquitination | Uniprot | |
| T468 | Phosphorylation | Uniprot | |
| K480 | Ubiquitination | Uniprot | |
| K490 | Ubiquitination | Uniprot | |
| T584 | Phosphorylation | Uniprot | |
| T594 | Phosphorylation | Uniprot | |
| K595 | Ubiquitination | Uniprot | |
| K714 | Ubiquitination | Uniprot | |
| K735 | Ubiquitination | Uniprot | |
| K803 | Ubiquitination | Uniprot | |
| K827 | Acetylation | Uniprot | |
| S873 | Phosphorylation | Uniprot | |
| K879 | Ubiquitination | Uniprot | |
| T881 | Phosphorylation | Uniprot |
研究背景
Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
Cytoplasm>Cytoskeleton>Microtubule organizing center>Centrosome.
Ubiquitously expressed.
Gamma-tubulin complex is composed of gamma-tubulin, TUBGCP2, TUBGCP3, TUBGCP4, TUBGCP5 and TUBGCP6. Interacts with ATF5; the ATF5:PCNT:polyglutamylated tubulin (PGT) tripartite unites the mother centriole and the pericentriolar material (PCM) in the centrosome.
Belongs to the TUBGCP family.
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