GNG2 Antibody - #DF9558
| 製品: | GNG2 Antibody |
| カタログ: | DF9558 |
| タンパク質の説明: | Rabbit polyclonal antibody to GNG2 |
| アプリケーション: | WB |
| 反応性: | Human, Mouse |
| 予測: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 8 kDa; 8kD(Calculated). |
| ユニプロット: | P59768 |
| RRID: | AB_2842754 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF9558, RRID:AB_2842754.
折りたたみ／展開
G gamma I; G gamma-I; GBG2_HUMAN; GNG 2; Gng2; Guanine nucleotide binding protein gamma 2; Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2;
免疫原
Expressed in fetal tissues, including testis, adrenal gland, brain, white blood cells and brain.
- P59768 GBG2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P59768 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| S3 | Phosphorylation | Uniprot | |
| T6 | Phosphorylation | Uniprot | |
| S8 | Phosphorylation | Uniprot | |
| K14 | Ubiquitination | Uniprot | |
| K20 | Ubiquitination | Uniprot | |
| K32 | Ubiquitination | Uniprot | |
| T52 | Phosphorylation | Uniprot |
研究背景
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction (By similarity).
Cell membrane>Lipid-anchor>Cytoplasmic side.
Expressed in fetal tissues, including testis, adrenal gland, brain, white blood cells and brain.
G proteins are composed of 3 units, alpha, beta and gamma (By similarity). The heterodimer formed by GNB1 and GNG2 interacts with ARHGEF5.
Belongs to the G protein gamma family.
研究領域
· Environmental Information Processing > Signal transduction > Ras signaling pathway. (View pathway)
· Environmental Information Processing > Signal transduction > PI3K-Akt signaling pathway. (View pathway)
· Environmental Information Processing > Signal transduction > Apelin signaling pathway. (View pathway)
· Human Diseases > Substance dependence > Morphine addiction.
· Human Diseases > Substance dependence > Alcoholism.
· Human Diseases > Cancers: Overview > Pathways in cancer. (View pathway)
· Organismal Systems > Immune system > Chemokine signaling pathway. (View pathway)
· Organismal Systems > Environmental adaptation > Circadian entrainment.
· Organismal Systems > Nervous system > Retrograde endocannabinoid signaling. (View pathway)
· Organismal Systems > Nervous system > Glutamatergic synapse.
· Organismal Systems > Nervous system > Cholinergic synapse.
· Organismal Systems > Nervous system > Serotonergic synapse.
· Organismal Systems > Nervous system > GABAergic synapse.
· Organismal Systems > Nervous system > Dopaminergic synapse.
· Organismal Systems > Endocrine system > Relaxin signaling pathway.
Restrictive clause
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