HEATR1 Antibody - #DF9569
(11)
製品説明
ソース:
Rabbit
アプリケーション:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
反応性:
Human,Mouse,Rat
予測:
Pig(100%), Horse(100%), Sheep(90%), Rabbit(80%), Dog(90%)
クローナリティ:
Polyclonal
特異性:
HEATR1 Antibody detects endogenous levels of total HEATR1.
RRID:
AB_2842765
引用形式: Affinity Biosciences Cat# DF9569, RRID:AB_2842765.
引用形式: Affinity Biosciences Cat# DF9569, RRID:AB_2842765.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:
折りたたみ／展開
BAP28; HEAT repeat containing 1; HEAT repeat containing protein 1; Protein BAP28; RP11-385F5.3; UTP10; UTP10 small subunit (SSU) processome component homolog;
免疫原
免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
- Q9H583 HEAT1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTSLAQQLQRLALPQSDASLLSRDEVASLLFDPKEAATIDRDTAFAIGCTGLEELLGIDPSFEQFEAPLFSQLAKTLERSVQTKAVNKQLDENISLFLIHLSPYFLLKPAQKCLEWLIHRFHIHLYNQDSLIACVLPYHETRIFVRVIQLLKINNSKHRWFWLLPVKQSGVPLAKGTLITHCYKDLGFMDFICSLVTKSVKVFAEYPGSSAQLRVLLAFYASTIVSALVAAEDVSDNIIAKLFPYIQKGLKSSLPDYRAATYMIICQISVKVTMENTFVNSLASQIIKTLTKIPSLIKDGLSCLIVLLQRQKPESLGKKPFPHLCNVPDLITILHGISETYDVSPLLHYMLPHLVVSIIHHVTGEETEGMDGQIYKRHLEAILTKISLKNNLDHLLASLLFEEYISYSSQEEMDSNKVSLLNEQFLPLIRLLESKYPRTLDVVLEEHLKEIADLKKQELFHQFVSLSTSGGKYQFLADSDTSLMLSLNHPLAPVRILAMNHLKKIMKTSKEGVDESFIKEAVLARLGDDNIDVVLSAISAFEIFKEHFSSEVTISNLLNLFQRAELSKNGEWYEVLKIAADILIKEEILSENDQLSNQVVVCLLPFMVINNDDTESAEMKIAIYLSKSGICSLHPLLRGWEEALENVIKSTKPGKLIGVANQKMIELLADNINLGDPSSMLKMVEDLISVGEEESFNLKQKVTFHVILSVLVSCCSSLKETHFPFAIRVFSLLQKKIKKLESVITAVEIPSEWHIELMLDRGIPVELWAHYVEELNSTQRVAVEDSVFLVFSLKKFIYALKAPKSFPKGDIWWNPEQLKEDSRDYLHLLIGLFEMMLNGADAVHFRVLMKLFIKVHLEDVFQLFKFCSVLWTYGSSLSNPLNCSVKTVLQTQALYVGCAMLSSQKTQCKHQLASISSPVVTSLLINLGSPVKEVRRAAIQCLQALSGVASPFYLIIDHLISKAEEITSDAAYVIQDLATLFEELQREKKLKSHQKLSETLKNLLSCVYSCPSYIAKDLMKVLQGVNGEMVLSQLLPMAEQLLEKIQKEPTAVLKDEAMVLHLTLGKYNEFSVSLLNEDPKSLDIFIKAVHTTKELYAGMPTIQITALEKITKPFFAAISDEKVQQKLLRMLFDLLVNCKNSHCAQTVSSVFKGISVNAEQVRIELEPPDKAKPLGTVQQKRRQKMQQKKSQDLESVQEVGGSYWQRVTLILELLQHKKKLRSPQILVPTLFNLLSRCLEPLPQEQGNMEYTKQLILSCLLNICQKLSPDGGKIPKDILDEEKFNVELIVQCIRLSEMPQTHHHALLLLGTVAGIFPDKVLHNIMSIFTFMGANVMRLDDTYSFQVINKTVKMVIPALIQSDSGDSIEVSRNVEEIVVKIISVFVDALPHVPEHRRLPILVQLVDTLGAEKFLWILLILLFEQYVTKTVLAAAYGEKDAILEADTEFWFSVCCEFSVQHQIQSLMNILQYLLKLPEEKEETIPKAVSFNKSESQEEMLQVFNVETHTSKQLRHFKFLSVSFMSQLLSSNNFLKKVVESGGPEILKGLEERLLETVLGYISAVAQSMERNADKLTVKFWRALLSKAYDLLDKVNALLPTETFIPVIRGLVGNPLPSVRRKALDLLNNKLQQNISWKKTIVTRFLKLVPDLLAIVQRKKKEGEEEQAINRQTALYTLKLLCKNFGAENPDPFVPVLNTAVKLIAPERKEEKNVLGSALLCIAEVTSTLEALAIPQLPSLMPSLLTTMKNTSELVSSEVYLLSALAALQKVVETLPHFISPYLEGILSQVIHLEKITSEMGSASQANIRLTSLKKTLATTLAPRVLLPAIKKTYKQIEKNWKNHMGPFMSILQEHIGVMKKEELTSHQSQLTAFFLEALDFRAQHSENDLEEVGKTENCIIDCLVAMVVKLSEVTFRPLFFKLFDWAKTEDAPKDRLLTFYNLADCIAEKLKGLFTLFAGHLVKPFADTLNQVNISKTDEAFFDSENDPEKCCLLLQFILNCLYKIFLFDTQHFISKERAEALMMPLVDQLENRLGGEEKFQERVTKHLIPCIAQFSVAMADDSLWKPLNYQILLKTRDSSPKVRFAALITVLALAEKLKENYIVLLPESIPFLAELMEDECEEVEHQCQKTIQQLETVLGEPLQSYF
種類予測
種類予測:
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
Species
Results
Score
Pig
100
Horse
100
Sheep
90
Dog
90
Rabbit
80
Bovine
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9H583 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| T2 | Acetylation | Uniprot | |
| T2 | Phosphorylation | Uniprot | |
| R10 | Methylation | Uniprot | |
| S16 | Phosphorylation | Uniprot | |
| S19 | Phosphorylation | Uniprot | |
| K34 | Ubiquitination | Uniprot | |
| K84 | Ubiquitination | Uniprot | |
| K175 | Ubiquitination | Uniprot | |
| K248 | Ubiquitination | Uniprot | |
| K292 | Ubiquitination | Uniprot | |
| T363 | Phosphorylation | Uniprot | |
| T367 | Phosphorylation | Uniprot | |
| Y375 | Phosphorylation | Uniprot | |
| K435 | Ubiquitination | Uniprot | |
| K503 | Ubiquitination | Uniprot | |
| K510 | Ubiquitination | Uniprot | |
| S516 | Phosphorylation | Uniprot | |
| K519 | Ubiquitination | Uniprot | |
| S539 | Phosphorylation | Uniprot | |
| K568 | Ubiquitination | Uniprot | |
| K627 | Ubiquitination | Uniprot | |
| K655 | Ubiquitination | Uniprot | |
| K663 | Ubiquitination | Uniprot | |
| S709 | Phosphorylation | Uniprot | |
| K801 | Ubiquitination | Uniprot | |
| K808 | Ubiquitination | Uniprot | |
| K909 | Ubiquitination | Uniprot | |
| S917 | Phosphorylation | Uniprot | |
| S929 | Phosphorylation | Uniprot | |
| K995 | Ubiquitination | Uniprot | |
| K1047 | Ubiquitination | Uniprot | |
| K1054 | Ubiquitination | Uniprot | |
| Y1067 | Phosphorylation | Uniprot | |
| K1093 | Ubiquitination | Uniprot | |
| T1105 | Phosphorylation | Uniprot | |
| K1112 | Ubiquitination | Uniprot | |
| S1119 | Phosphorylation | Uniprot | |
| K1122 | Ubiquitination | Uniprot | |
| K1152 | Ubiquitination | Uniprot | |
| K1170 | Ubiquitination | Uniprot | |
| K1172 | Ubiquitination | Uniprot | |
| K1180 | Ubiquitination | Uniprot | |
| K1189 | Ubiquitination | Uniprot | |
| S1190 | Phosphorylation | Uniprot | |
| S1195 | Phosphorylation | Uniprot | |
| K1272 | Ubiquitination | Uniprot | |
| K1275 | Ubiquitination | Uniprot | |
| T1340 | Phosphorylation | Uniprot | |
| Y1341 | Phosphorylation | Uniprot | |
| S1360 | Phosphorylation | Uniprot | |
| K1477 | Ubiquitination | Uniprot | |
| K1483 | Ubiquitination | Uniprot | |
| S1486 | Phosphorylation | Uniprot | |
| K1489 | Ubiquitination | Uniprot | |
| S1490 | Phosphorylation | Uniprot | |
| S1492 | Phosphorylation | Uniprot | |
| K1508 | Ubiquitination | Uniprot | |
| S1517 | Phosphorylation | Uniprot | |
| S1519 | Phosphorylation | Uniprot | |
| S1526 | Phosphorylation | Uniprot | |
| S1527 | Phosphorylation | Uniprot | |
| K1533 | Ubiquitination | Uniprot | |
| S1537 | Phosphorylation | Uniprot | |
| K1575 | Ubiquitination | Uniprot | |
| T1597 | Phosphorylation | Uniprot | |
| T1599 | Phosphorylation | Uniprot | |
| S1614 | Phosphorylation | Uniprot | |
| K1618 | Ubiquitination | Uniprot | |
| K1626 | Ubiquitination | Uniprot | |
| K1634 | Ubiquitination | Uniprot | |
| K1655 | Acetylation | Uniprot | |
| K1675 | Ubiquitination | Uniprot | |
| K1679 | Acetylation | Uniprot | |
| K1679 | Ubiquitination | Uniprot | |
| S1794 | Phosphorylation | Uniprot | |
| K1811 | Ubiquitination | Uniprot | |
| T1815 | Phosphorylation | Uniprot | |
| T1816 | Phosphorylation | Uniprot | |
| R1820 | Methylation | Uniprot | |
| K1831 | Acetylation | Uniprot | |
| K1831 | Ubiquitination | Uniprot | |
| K1835 | Ubiquitination | Uniprot | |
| S1882 | Phosphorylation | Uniprot | |
| K1924 | Ubiquitination | Uniprot | |
| S1981 | Phosphorylation | Uniprot | |
| T2007 | Phosphorylation | Uniprot | |
| S2012 | Phosphorylation | Uniprot | |
| K2036 | Ubiquitination | Uniprot | |
| S2076 | Phosphorylation | Uniprot | |
| T2087 | Phosphorylation | Uniprot |
研究背景
機能:
Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I.
細胞の位置付け:
Nucleus>Nucleolus.
サブユニット構造:
May be a component of the proposed t-UTP subcomplex of the ribosomal small subunit (SSU) processome containing at least UTP4, WDR43, HEATR1, UTP15, WDR75.
タンパク質ファミリー:
Belongs to the HEATR1/UTP10 family.
研究領域
· Genetic Information Processing > Translation > Ribosome biogenesis in eukaryotes.
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