製品: KIR2DL2 Antibody
カタログ: DF9599
タンパク質の説明: Rabbit polyclonal antibody to KIR2DL2
アプリケーション: WB
反応性: Human, Mouse
分子量: 38 kDa; 38kD(Calculated).
ユニプロット: P43627
RRID: AB_2842795

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 100ul $280 在庫あり
 200ul $350 在庫あり

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
クローナリティ:
Polyclonal
特異性:
KIR2DL2 Antibody detects endogenous levels of total KIR2DL2.
RRID:
AB_2842795
引用形式: Affinity Biosciences Cat# DF9599, RRID:AB_2842795.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

CD158 antigen-like family member B1; CD158b; CD158b1; KI2L2_HUMAN; Killer cell immunoglobulin like receptor two domains long cytoplasmic tail 2; Killer cell immunoglobulin-like receptor 2DL2; KIR2DL2; MHC class I NK cell receptor; Natural killer-associated transcript 6; NKAT 6; NKAT-6; NKAT6; p58 natural killer cell receptor clone CL-43; p58 NK receptor CL-43; p58.2;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVIGNPSNSWPSPTEPSSKTGNPRHLHILIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYAELPNAESRSKVVSCP

PTMs - P43627 基板として

Site PTM Type Enzyme
S30 Phosphorylation
S86 Phosphorylation
Y98 Phosphorylation
T138 Phosphorylation
S150 Phosphorylation
S151 Phosphorylation
T180 Phosphorylation
S281 Phosphorylation
Y302 Phosphorylation
T311 Phosphorylation

研究背景

機能:

Receptor on natural killer (NK) cells for HLA-Cw1, 3, 7, and 8 allotypes. Inhibits the activity of NK cells thus preventing cell lysis.

細胞の位置付け:

Cell membrane>Single-pass type I membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
タンパク質ファミリー:

Belongs to the immunoglobulin superfamily.

研究領域

· Cellular Processes > Cell growth and death > Cellular senescence.   (View pathway)

· Human Diseases > Immune diseases > Graft-versus-host disease.

· Organismal Systems > Immune system > Antigen processing and presentation.   (View pathway)

· Organismal Systems > Immune system > Natural killer cell mediated cytotoxicity.   (View pathway)

Restrictive clause

 

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For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.