MYH3 Antibody - #DF9647
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF9647, RRID:AB_2842843.
折りたたみ／展開
adult 1; MYH1; MYH1_HUMAN; MYH2; MYH3; MYH4; MYH6; MyHC-2x; MyHC-IIx/d; MYL1; MYL2; MYL3; MYL5; MYL6; Myosin light chain 2 regulatory cardiac slow; Myosin 1; Myosin heavy chain 1; Myosin heavy chain 1 skeletal muscle adult; Myosin heavy chain 2 skeletal muscle adult; Myosin heavy chain 2x; Myosin heavy chain 3 skeletal muscle adult; Myosin heavy chain 4 skeletal muscle adult; Myosin heavy chain 6 skeletal muscle adult; Myosin heavy chain; Myosin heavy chain IIx/d; Myosin heavy chain skeletal muscle adult 1; Myosin II; Myosin light chain 1 alkali skeletal fast; Myosin light chain 3 alkali ventricular skeletal slow; Myosin light chain 4 alkali atrial embryonic; Myosin light chain 5 regulatory; Myosin light chain 6 alkali smooth muscle and non muscle; Myosin-1; Myosin1; skeletal muscle;
免疫原
- P11055 MYH3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSSDTEMEVFGIAAPFLRKSEKERIEAQNQPFDAKTYCFVVDSKEEYAKGKIKSSQDGKVTVETEDNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLAKKKDSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIELLLITTNPYDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHLYATFATADADSGKKKVAKKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDFTSSRMVVHESEE
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P11055 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K44 | Acetylation | Uniprot | |
| Y78 | Phosphorylation | Uniprot | |
| Y110 | Phosphorylation | Uniprot | |
| Y163 | Phosphorylation | Uniprot | |
| T168 | Phosphorylation | Uniprot | |
| K247 | Ubiquitination | Uniprot | |
| T256 | Phosphorylation | Uniprot | |
| S261 | Phosphorylation | Uniprot | |
| Y267 | Phosphorylation | Uniprot | |
| K271 | Ubiquitination | Uniprot | |
| T354 | Phosphorylation | Uniprot | |
| Y360 | Phosphorylation | Uniprot | |
| T379 | Phosphorylation | Uniprot | |
| Y411 | Phosphorylation | Uniprot | |
| T413 | Phosphorylation | Uniprot | |
| K414 | Acetylation | Uniprot | |
| K503 | Acetylation | Uniprot | |
| Y554 | Phosphorylation | Uniprot | |
| Y610 | Phosphorylation | Uniprot | |
| Y716 | Phosphorylation | Uniprot | |
| Y723 | Phosphorylation | Uniprot | |
| S729 | Phosphorylation | Uniprot | |
| S739 | Phosphorylation | Uniprot | |
| Y817 | Phosphorylation | Uniprot | |
| K832 | Acetylation | Uniprot | |
| K842 | Acetylation | Uniprot | |
| T852 | Phosphorylation | Uniprot | |
| T860 | Phosphorylation | Uniprot | |
| K872 | Acetylation | Uniprot | |
| S949 | Phosphorylation | Uniprot | |
| K952 | Acetylation | Uniprot | |
| K953 | Acetylation | Uniprot | |
| T961 | Phosphorylation | Uniprot | |
| S984 | Phosphorylation | Uniprot | |
| S1066 | Phosphorylation | Uniprot | |
| T1129 | Phosphorylation | Uniprot | |
| T1133 | Phosphorylation | Uniprot | |
| S1138 | Phosphorylation | Uniprot | |
| Y1140 | Phosphorylation | Uniprot | |
| S1200 | Phosphorylation | Uniprot | |
| S1336 | Phosphorylation | Uniprot | |
| S1367 | Phosphorylation | Uniprot | |
| T1374 | Phosphorylation | Uniprot | |
| Y1376 | Phosphorylation | Uniprot | |
| T1378 | Phosphorylation | Uniprot | |
| T1384 | Phosphorylation | Uniprot | |
| K1391 | Acetylation | Uniprot | |
| K1392 | Acetylation | Uniprot | |
| K1393 | Acetylation | Uniprot | |
| T1418 | Phosphorylation | Uniprot | |
| S1477 | Phosphorylation | Uniprot | |
| S1479 | Phosphorylation | Uniprot | |
| T1480 | Phosphorylation | Uniprot | |
| Y1489 | Phosphorylation | Uniprot | |
| T1733 | Phosphorylation | Uniprot | |
| S1740 | Phosphorylation | Uniprot | |
| T1761 | Phosphorylation | Uniprot | |
| K1771 | Acetylation | Uniprot | |
| K1832 | Acetylation | Uniprot | |
| K1877 | Acetylation | Uniprot | |
| K1880 | Acetylation | Uniprot | |
| S1916 | Phosphorylation | Uniprot |
研究背景
Muscle contraction.
Cytoplasm>Myofibril.
Note: Thick filaments of the myofibrils.
Expressed in fetal bone, thymus, placenta, heart, brain, and liver.
Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2).
The rodlike tail sequence is highly repetitive, showing cycles of a 28-residue repeat pattern composed of 4 heptapeptides, characteristic for alpha-helical coiled coils.
Limited proteolysis of myosin heavy chain produces 1 light meromyosin (LMM) and 1 heavy meromyosin (HMM). HMM can be further cleaved into 2 globular subfragments (S1) and 1 rod-shaped subfragment (S2).
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
研究領域
· Cellular Processes > Cellular community - eukaryotes > Tight junction. (View pathway)
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