MYH8 Antibody - #DF9648

(1)  
製品: MYH8 Antibody
カタログ: DF9648
タンパク質の説明: Rabbit polyclonal antibody to MYH8
アプリケーション: WB
反応性: Human
予測: Pig, Horse, Rabbit, Dog
分子量: 223kDa; 223kD(Calculated).
ユニプロット: P13535
RRID: AB_2842844

類似製品を見る>>

   サイズ 価格 在庫状況
 100ul $280 在庫あり
 200ul $350 在庫あり

リードタイム: 当日配達

For pricing and ordering contact:
お問い合わせ先
関連ダウンロード
MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
予測:
Pig(92%), Horse(100%), Rabbit(100%), Dog(83%)
クローナリティ:
Polyclonal
特異性:
MYH8 Antibody detects endogenous levels of total MYH8.
RRID:
AB_2842844
引用形式: Affinity Biosciences Cat# DF9648, RRID:AB_2842844.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

DA7; Fetal myosin heavy chain; gtMHC F; MYH8; MYH8_HUMAN; MyHC peri; MyHC pn; MyHC-perinatal; Myosin heavy chain 8; Myosin heavy chain; Myosin heavy chain, skeletal muscle, perinatal; Myosin, heavy chain 8, skeletal muscle, perinatal; Myosin, heavy polypeptide 8, skeletal muscle, perinatal; Myosin-8; perinatal; skeletal muscle;

免疫原

免疫原:
Uniprot:

P13535(MYH8_HUMAN) >>Visit HPA database.

遺伝子(ID):
MYH8(4626)
タンパク質配列:
MSASSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSTIQSKEGGKVTVKTEGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKDESGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKTLASLFSTYASAEADSSAKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKISAE

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Rabbit
100
Horse
100
Pig
92
Dog
83
Bovine
75
Sheep
75
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P13535 基板として

Site PTM Type Enzyme
T63 Phosphorylation
T73 Phosphorylation
Y165 Phosphorylation
T170 Phosphorylation
Y197 Phosphorylation
T200 Phosphorylation
K249 Ubiquitination
T258 Phosphorylation
S263 Phosphorylation
Y269 Phosphorylation
K273 Ubiquitination
S351 Phosphorylation
Y353 Phosphorylation
T356 Phosphorylation
Y362 Phosphorylation
T381 Phosphorylation
Y389 Phosphorylation
Y404 Phosphorylation
Y413 Phosphorylation
T415 Phosphorylation
K416 Acetylation
Y424 Phosphorylation
K505 Acetylation
Y556 Phosphorylation
Y591 Phosphorylation
T663 Phosphorylation
S731 Phosphorylation
S741 Phosphorylation
K743 Acetylation
S745 Phosphorylation
T791 Phosphorylation
Y819 Phosphorylation
K834 Acetylation
K844 Acetylation
T854 Phosphorylation
T862 Phosphorylation
K874 Acetylation
S951 Phosphorylation
K954 Acetylation
K955 Acetylation
T963 Phosphorylation
K979 Acetylation
T982 Phosphorylation
T991 Phosphorylation
K994 Acetylation
K1000 Ubiquitination
S1040 Phosphorylation
K1045 Acetylation
S1140 Phosphorylation
S1143 Phosphorylation
K1169 Ubiquitination
K1176 Ubiquitination
K1222 Ubiquitination
S1236 Phosphorylation
T1277 Phosphorylation
S1302 Phosphorylation
S1338 Phosphorylation
S1369 Phosphorylation
T1376 Phosphorylation
Y1378 Phosphorylation
T1380 Phosphorylation
T1386 Phosphorylation
K1393 Acetylation
K1394 Acetylation
K1395 Acetylation
T1420 Phosphorylation
Y1463 Phosphorylation
T1466 Phosphorylation
S1477 Phosphorylation
S1479 Phosphorylation
S1481 Phosphorylation
T1482 Phosphorylation
S1513 Phosphorylation
T1516 Phosphorylation
S1573 Phosphorylation
S1602 Phosphorylation
T1603 Phosphorylation
Y1646 Phosphorylation
T1649 Phosphorylation
S1701 Phosphorylation
S1713 Phosphorylation
T1721 Phosphorylation
T1724 Phosphorylation
S1725 Phosphorylation
T1729 Phosphorylation
K1730 Acetylation
T1763 Phosphorylation
K1773 Acetylation
T1854 Phosphorylation
Y1855 Phosphorylation
K1862 Acetylation
S1918 Phosphorylation
K1933 Acetylation

研究背景

機能:

Muscle contraction.

細胞の位置付け:

Cytoplasm>Myofibril.
Note: Thick filaments of the myofibrils.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2).

タンパク質ファミリー:

The rodlike tail sequence is highly repetitive, showing cycles of a 28-residue repeat pattern composed of 4 heptapeptides, characteristic for alpha-helical coiled coils.

Limited proteolysis of myosin heavy chain produces 1 light meromyosin (LMM) and 1 heavy meromyosin (HMM). HMM can be further cleaved into 2 globular subfragments (S1) and 1 rod-shaped subfragment (S2).

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

研究領域

· Cellular Processes > Cellular community - eukaryotes > Tight junction.   (View pathway)

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.