NDUFA5 Antibody - #DF9660
| 製品: | NDUFA5 Antibody |
| カタログ: | DF9660 |
| タンパク質の説明: | Rabbit polyclonal antibody to NDUFA5 |
| アプリケーション: | WB |
| 反応性: | Human, Mouse |
| 予測: | Pig, Zebrafish, Bovine, Dog |
| 分子量: | 13 kDa; 13kD(Calculated). |
| ユニプロット: | Q16718 |
| RRID: | AB_2842856 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF9660, RRID:AB_2842856.
折りたたみ／展開
B13; CI 13kB; CI-13kD-B; Complex I subunit B13; Complex I-13kD-B; DKFZp781K1356; FLJ12147; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 (13kD, B13); NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5; NADH-ubiquinone oxidoreductase 13 kDa-B subunit; NDUA5_HUMAN; NDUFA5; NUFM; Type I dehydrogenase; Ubiquinone reductase; UQOR13;
免疫原
Expressed in all tissues examined with highest levels in heart, skeletal muscle and brain.
- Q16718 NDUA5_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAGVLKKTTGLVGLAVCNTPHERLRILYTKILDVLEEIPKNAAYRKYTEQITNEKLAMVKAEPDVKKLEDQLQGGQLEEVILQAEHELNLARKMREWKLWEPLVEEPPADQWKWPI
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q16718 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| C17 | S-Nitrosylation | Uniprot | |
| Y28 | Phosphorylation | Uniprot | |
| K30 | Acetylation | Uniprot | |
| K60 | Acetylation | Uniprot | |
| K60 | Sumoylation | Uniprot |
研究背景
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Mitochondrion inner membrane>Peripheral membrane protein>Matrix side.
Expressed in all tissues examined with highest levels in heart, skeletal muscle and brain.
Complex I is composed of 45 different subunits.
Belongs to the complex I NDUFA5 subunit family.
研究領域
· Human Diseases > Endocrine and metabolic diseases > Non-alcoholic fatty liver disease (NAFLD).
· Human Diseases > Neurodegenerative diseases > Alzheimer's disease.
· Human Diseases > Neurodegenerative diseases > Parkinson's disease.
· Human Diseases > Neurodegenerative diseases > Huntington's disease.
· Metabolism > Energy metabolism > Oxidative phosphorylation.
· Metabolism > Global and overview maps > Metabolic pathways.
· Organismal Systems > Nervous system > Retrograde endocannabinoid signaling. (View pathway)
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