NDUFA6 Antibody - #DF9661
| 製品: | NDUFA6 Antibody |
| カタログ: | DF9661 |
| タンパク質の説明: | Rabbit polyclonal antibody to NDUFA6 |
| アプリケーション: | WB |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 18 kDa; 15kD(Calculated). |
| ユニプロット: | P56556 |
| RRID: | AB_2842857 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF9661, RRID:AB_2842857.
折りたたみ／展開
B14; CI-B14; complex I B14 subunit; Complex I-B14; LYR motif-containing protein 6; LYRM6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6 (14kD, B14); NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6; NADH-ubiquinone oxidoreductase 1 alpha subcomplex, 6; NADH-ubiquinone oxidoreductase B14 subunit; NADHB14; NDUA6_HUMAN; NDUFA6;
免疫原
- P56556 NDUA6_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAGSGVRQATSTASTFVKPIFSRDMNEAKRRVRELYRAWYREVPNTVHQFQLDITVKMGRDKVREMFMKNAHVTDPRVVDLLVIKGKIELEETIKVWKQRTHVMRFFHETEAPRPKDFLSKFYVGHDP
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P56556 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S11 | Phosphorylation | Uniprot | |
| K18 | Ubiquitination | Uniprot | |
| R77 | Methylation | Uniprot | |
| K85 | Ubiquitination | Uniprot | |
| T93 | Phosphorylation | Uniprot | |
| K116 | Ubiquitination | Uniprot | |
| K121 | Ubiquitination | Uniprot |
研究背景
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Required for proper complex I assembly. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Mitochondrion inner membrane>Peripheral membrane protein>Matrix side.
Mammalian complex I is composed of 45 different subunits.
Belongs to the complex I LYR family.
研究領域
· Human Diseases > Endocrine and metabolic diseases > Non-alcoholic fatty liver disease (NAFLD).
· Human Diseases > Neurodegenerative diseases > Alzheimer's disease.
· Human Diseases > Neurodegenerative diseases > Parkinson's disease.
· Human Diseases > Neurodegenerative diseases > Huntington's disease.
· Metabolism > Energy metabolism > Oxidative phosphorylation.
· Metabolism > Global and overview maps > Metabolic pathways.
· Organismal Systems > Nervous system > Retrograde endocannabinoid signaling. (View pathway)
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