製品: NDUFA7 Antibody
カタログ: DF9662
タンパク質の説明: Rabbit polyclonal antibody to NDUFA7
アプリケーション: WB
反応性: Human, Mouse, Rat
予測: Pig, Zebrafish, Bovine, Sheep, Dog, Chicken, Xenopus
分子量: 13 kDa; 13kD(Calculated).
ユニプロット: O95182
RRID: AB_2842858

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Zebrafish(82%), Bovine(100%), Sheep(91%), Dog(100%), Chicken(82%), Xenopus(90%)
クローナリティ:
Polyclonal
特異性:
NDUFA7 Antibody detects endogenous levels of total NDUFA7.
RRID:
AB_2842858
引用形式: Affinity Biosciences Cat# DF9662, RRID:AB_2842858.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

B14.5a; CI-B14.5a; Complex I B14.5a; Complex I-B14.5a; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 7 14.5kDa; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7; NADH ubiquinone oxidoreductase subunit B14.5a; NADH-ubiquinone oxidoreductase subunit B14.5a; NDUA7_HUMAN; NDUFA7;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MASATRLIQRLRNWASGHDLQGKLQLRYQEISKRTQPPPKLPVGPSHKLSNNYYCTRDGRRESVPPSIIMSSQKALVSGKPAESSAVAATEKKAVTPAPPIKRWELSSDQPYL

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Dog
100
Sheep
91
Xenopus
90
Zebrafish
82
Chicken
82
Horse
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O95182 基板として

Site PTM Type Enzyme
R12 Methylation
K23 Ubiquitination
S32 Phosphorylation
Y53 Phosphorylation
S63 Phosphorylation
S67 Phosphorylation
S85 Phosphorylation
T90 Phosphorylation
T96 Phosphorylation

研究背景

機能:

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

細胞の位置付け:

Mitochondrion inner membrane>Peripheral membrane protein>Matrix side.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Complex I is composed of 45 different subunits.

タンパク質ファミリー:

Belongs to the complex I NDUFA7 subunit family.

研究領域

· Human Diseases > Endocrine and metabolic diseases > Non-alcoholic fatty liver disease (NAFLD).

· Human Diseases > Neurodegenerative diseases > Alzheimer's disease.

· Human Diseases > Neurodegenerative diseases > Parkinson's disease.

· Human Diseases > Neurodegenerative diseases > Huntington's disease.

· Metabolism > Energy metabolism > Oxidative phosphorylation.

· Metabolism > Global and overview maps > Metabolic pathways.

· Organismal Systems > Nervous system > Retrograde endocannabinoid signaling.   (View pathway)

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For Research Use Only.
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