NDUFV1 Antibody - #DF9668
| 製品: | NDUFV1 Antibody |
| カタログ: | DF9668 |
| タンパク質の説明: | Rabbit polyclonal antibody to NDUFV1 |
| アプリケーション: | WB |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Zebrafish, Bovine, Horse, Sheep, Dog, Chicken, Xenopus |
| 分子量: | 51 kDa; 51kD(Calculated). |
| ユニプロット: | P49821 |
| RRID: | AB_2842864 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF9668, RRID:AB_2842864.
折りたたみ／展開
CI 51kD; CI-51kD; CI51KD; Complex I 51kD; Complex I-51kD; FLJ59059; mitochondrial; NADH dehydrogenase (ubiquinone) flavoprotein 1; NADH dehydrogenase [ubiquinone] flavoprotein 1; NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; NADH dehydrogenase flavoprotein 1; NADH ubiquinone oxidoreductase 51 kDa subunit; NADH ubiquinone oxidoreductase; NADH ubiquinone oxidoreductase core subunit V1; NADH-ubiquinone oxidoreductase 51 kDa subunit; NDUFV 1; ndufv1; NDUV1_HUMAN; UQOR1;
免疫原
- P49821 NDUV1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLATRRLLGWSLPARVSVRFSGDTTAPKKTSFGSLKDEDRIFTNLYGRHDWRLKGSLSRGDWYKTKEILLKGPDWILGEIKTSGLRGRGGAGFPTGLKWSFMNKPSDGRPKYLVVNADEGEPGTCKDREILRHDPHKLLEGCLVGGRAMGARAAYIYIRGEFYNEASNLQVAIREAYEAGLIGKNACGSGYDFDVFVVRGAGAYICGEETALIESIEGKQGKPRLKPPFPADVGVFGCPTTVANVETVAVSPTICRRGGTWFAGFGRERNSGTKLFNISGHVNHPCTVEEEMSVPLKELIEKHAGGVTGGWDNLLAVIPGGSSTPLIPKSVCETVLMDFDALVQAQTGLGTAAVIVMDRSTDIVKAIARLIEFYKHESCGQCTPCREGVDWMNKVMARFVRGDARPAEIDSLWEISKQIEGHTICALGDGAAWPVQGLIRHFRPELEERMQRFAQQHQARQAAS
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P49821 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K29 | Ubiquitination | Uniprot | |
| R40 | Methylation | Uniprot | |
| K64 | Acetylation | Uniprot | |
| K66 | Ubiquitination | Uniprot | |
| K71 | Ubiquitination | Uniprot | |
| K81 | Acetylation | Uniprot | |
| K81 | Ubiquitination | Uniprot | |
| R88 | Methylation | Uniprot | |
| K111 | Ubiquitination | Uniprot | |
| T124 | Phosphorylation | Uniprot | |
| K126 | Ubiquitination | Uniprot | |
| K137 | Ubiquitination | Uniprot | |
| S251 | Phosphorylation | Uniprot | |
| R257 | Methylation | Uniprot | |
| K297 | Ubiquitination | Uniprot | |
| S323 | Phosphorylation | Uniprot | |
| T324 | Phosphorylation | Uniprot | |
| K365 | Ubiquitination | Uniprot | |
| K375 | Acetylation | Uniprot | |
| K375 | Ubiquitination | Uniprot | |
| T383 | Phosphorylation | Uniprot | |
| K394 | Ubiquitination | Uniprot | |
| S464 | Phosphorylation | Uniprot |
研究背景
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
Mitochondrion inner membrane>Peripheral membrane protein>Matrix side.
Complex I is composed of 45 different subunits. This is a component of the flavoprotein-sulfur (FP) fragment of the enzyme. Interacts with RAB5IF.
Belongs to the complex I 51 kDa subunit family.
研究領域
· Human Diseases > Endocrine and metabolic diseases > Non-alcoholic fatty liver disease (NAFLD).
· Human Diseases > Neurodegenerative diseases > Alzheimer's disease.
· Human Diseases > Neurodegenerative diseases > Parkinson's disease.
· Human Diseases > Neurodegenerative diseases > Huntington's disease.
· Metabolism > Energy metabolism > Oxidative phosphorylation.
· Metabolism > Global and overview maps > Metabolic pathways.
· Organismal Systems > Nervous system > Retrograde endocannabinoid signaling. (View pathway)
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