NDUFS6 Antibody - #DF9671
| 製品: | NDUFS6 Antibody |
| カタログ: | DF9671 |
| タンパク質の説明: | Rabbit polyclonal antibody to NDUFS6 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Zebrafish, Bovine, Horse, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 14 kDa; 14kD(Calculated). |
| ユニプロット: | O75380 |
| RRID: | AB_2842867 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF9671, RRID:AB_2842867.
折りたたみ／展開
BC059730; CI 13kA; CI 13kD A; CI-13kD-A; CI13KDA; Complex I 13kD A; Complex I 13kDa subunit A; Complex I mitochondrial respiratory chain 13 kD subunit; Complex I-13kD-A; IP13; MGC107676; NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron sulfur protein 6, mitochondrial; NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; NADH ubiquinone oxidoreductase 13 kDa A subunit; NADH-ubiquinone oxidoreductase 13 kDa-A subunit; NADH:ubiquinone oxidoreductase NDUFS6 subunit; NADH:ubiquinone oxidoreductase subunit S6; Ndufs6; NDUS6_HUMAN;
免疫原
- O75380 NDUS6_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAAMTFCRLLNRCGEAARSLPLGARCFGVRVSPTGEKVTHTGQVYDDKDYRRIRFVGRQKEVNENFAIDLIAEQPVSEVETRVIACDGGGGALGHPKVYINLDKETKTGTCGYCGLQFRQHHH
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O75380 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| C27 | S-Nitrosylation | Uniprot | |
| K38 | Ubiquitination | Uniprot | |
| K49 | Ubiquitination | Uniprot | |
| Y51 | Phosphorylation | Uniprot | |
| S78 | Phosphorylation | Uniprot | |
| T82 | Phosphorylation | Uniprot | |
| K98 | Acetylation | Uniprot | |
| Y100 | Phosphorylation | Uniprot | |
| K105 | Ubiquitination | Uniprot |
研究背景
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Mitochondrion inner membrane>Peripheral membrane protein>Matrix side.
Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
Belongs to the complex I NDUFS6 subunit family.
研究領域
· Human Diseases > Endocrine and metabolic diseases > Non-alcoholic fatty liver disease (NAFLD).
· Human Diseases > Neurodegenerative diseases > Alzheimer's disease.
· Human Diseases > Neurodegenerative diseases > Parkinson's disease.
· Human Diseases > Neurodegenerative diseases > Huntington's disease.
· Metabolism > Energy metabolism > Oxidative phosphorylation.
· Metabolism > Global and overview maps > Metabolic pathways.
· Organismal Systems > Nervous system > Retrograde endocannabinoid signaling. (View pathway)
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