製品: CYB5R2 Antibody
カタログ: DF9673
タンパク質の説明: Rabbit polyclonal antibody to CYB5R2
アプリケーション: WB IHC
反応性: Human, Mouse, Rat
予測: Horse, Rabbit, Dog
分子量: 31 kDa; 31kD(Calculated).
ユニプロット: Q6BCY4
RRID: AB_2842869

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Horse(82%), Rabbit(82%), Dog(82%)
クローナリティ:
Polyclonal
特異性:
CYB5R2 Antibody detects endogenous levels of total CYB5R2.
RRID:
AB_2842869
引用形式: Affinity Biosciences Cat# DF9673, RRID:AB_2842869.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

b5R.2; Cyb5r2; Cytochrome b5 reductase 2; Cytochrome b5 reductase b5R.2; NADH cytochrome b5 reductase 2; NADH-cytochrome b5 reductase 2; NB5R2_HUMAN;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q6BCY4 NB5R2_HUMAN:

Restricted expression.

タンパク質配列:
MNSRRREPITLQDPEAKYPLPLIEKEKISHNTRRFRFGLPSPDHVLGLPVGNYVQLLAKIDNELVVRAYTPVSSDDDRGFVDLIIKIYFKNVHPQYPEGGKMTQYLENMKIGETIFFRGPRGRLFYHGPGNLGIRPDQTSEPKKTLADHLGMIAGGTGITPMLQLIRHITKDPSDRTRMSLIFANQTEEDILVRKELEEIARTHPDQFNLWYTLDRPPIGWKYSSGFVTADMIKEHLPPPAKSTLILVCGPPPLIQTAAHPNLEKLGYTQDMIFTY

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Horse
82
Dog
82
Rabbit
82
Chicken
73
Xenopus
64
Pig
0
Bovine
0
Sheep
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q6BCY4 基板として

Site PTM Type Enzyme
S41 Phosphorylation
T145 Phosphorylation
T157 Phosphorylation
T177 Phosphorylation

研究背景

機能:

NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction (By similarity). Responsible for NADH-dependent lucigenin chemiluminescence in spermatozoa by reducing both lucigenin and 2-[4-iodophenyl]-3-[4-nitrophenyl]-5-[2,4-disulfophenyl]-2H tetrazolium monosodium salt (WST-1).

組織特異性:

Restricted expression.

タンパク質ファミリー:

Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

研究領域

· Metabolism > Carbohydrate metabolism > Amino sugar and nucleotide sugar metabolism.

Restrictive clause

 

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