製品: NUP205 Antibody
カタログ: DF9709
タンパク質の説明: Rabbit polyclonal antibody to NUP205
アプリケーション: WB IHC
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
分子量: 228 kDa; 228kD(Calculated).
ユニプロット: Q92621
RRID: AB_2842904

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 100ul $280 在庫あり
 200ul $350 在庫あり

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製品説明

ソース:
Rabbit
アプリケーション:
IHC 1:50-1:200, WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(88%), Bovine(88%), Horse(88%), Sheep(88%), Rabbit(88%), Dog(100%), Chicken(88%), Xenopus(88%)
クローナリティ:
Polyclonal
特異性:
NUP205 Antibody detects endogenous levels of total NUP205.
RRID:
AB_2842904
引用形式: Affinity Biosciences Cat# DF9709, RRID:AB_2842904.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

205 kDa nucleoporin; C7orf14; KIAA0225; NU205_HUMAN; Nuclear pore complex protein Nup205; Nucleoporin Nup205; NUP205;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MATPLAVNSAASLWGPYKDIWHKVGNALWRRQPEAVHLLDKILKKHKPDFISLFKNPPKNVQQHEKVQKASTEGVAIQGQQGTRLLPEQLIKEAFILSDLFDIGELAAVELLLAGEHQQPHFPGLTRGLVAVLLYWDGKRCIANSLKALIQSRRGKTWTLELSPELASMTTRFTDELMEQGLTYKVLTLVSQIDVNNEFEKLQRERGLGSEKHRKEVSDLIKECRQSLAESLFAWACQSPLGKEDTLLLIGHLERVTVEANGSLDAVNLALLMALLYCFDISFIEQSTEERDDMIHQLPLLTEKQYIATIHSRLQDSQLWKLPGLQATVRLAWALALRGISQLPDVTALAEFTEADEAMAELAIADNVFLFLMESVVVSEYFYQEEFYIRRVHNLITDFLALMPMKVKQLRNRADEDARMIHMSMQMGNEPPISLRRDLEHLMLLIGELYKKNPFHLELALEYWCPTEPLQTPTIMGSYLGVAHQRPPQRQVVLSKFVRQMGDLLPPTIYIPYLKMLQGLANGPQCAHYCFSLLKVNGSSHVENIQGAGGSPVSWEHFFHSLMLYHEHLRKDLPSADSVQYRHLPSRGITQKEQDGLIAFLQLTSTIITWSENARLALCEHPQWTPVVVILGLLQCSIPPVLKAELLKTLAAFGKSPEIAASLWQSLEYTQILQTVRIPSQRQAIGIEVELNEIESRCEEYPLTRAFCQLISTLVESSFPSNLGAGLRPPGFDPYLQFLRDSVFLRFRTRAYRRAAEKWEVAEVVLEVFYKLLRDYEPQLEDFVDQFVELQGEEIIAYKPPGFSLMYHLLNESPMLELALSLLEEGVKQLDTYAPFPGKKHLEKAVQHCLALLNLTLQKENLFMDLLRESQLALIVCPLEQLLQGINPRTKKADNVVNIARYLYHGNTNPELAFESAKILCCISCNSNIQIKLVGDFTHDQSISQKLMAGFVECLDCEDAEEFVRLEEGSELEKKLVAIRHETRIHILNLLITSLECNPPNLALYLLGFELKKPVSTTNLQDPGVLGCPRTCLHAILNILEKGTEGRTGPVAVRESPQLAELCYQVIYQLCACSDTSGPTMRYLRTSQDFLFSQLQYLPFSNKEYEISMLNQMSWLMKTASIELRVTSLNRQRSHTQRLLHLLLDDMPVKPYSDGEGGIEDENRSVSGFLHFDTATKVRRKILNILDSIDFSQEIPEPLQLDFFDRAQIEQVIANCEHKNLRGQTVCNVKLLHRVLVAEVNALQGMAAIGQRPLLMEEISTVLQYVVGRNKLLQCLHAKRHALESWRQLVEIILTACPQDLIQAEDRQLIIRDILQDVHDKILDDEAAQELMPVVAGAVFTLTAHLSQAVLTEQKETSVLGPAEAHYAFMLDSCFTSPPPEENPLVGFASIGDSSLYIILKKLLDFILKTGGGFQRVRTHLYGSLLYYLQIAQRPDEPDTLEAAKKTMWERLTAPEDVFSKLQRENIAIIESYGAALMEVVCRDACDGHEIGRMLALALLDRIVSVDKQQQWLLYLSNSGYLKVLVDSLVEDDRTLQSLLTPQPPLLKALYTYESKMAFLTRVAKIQQGALELLRSGVIVRLAQCQVYDMRPETDPQSMFGMRDPPMFIPTPVDRYRQILLPALQLCQVILTSSMAQHLQAAGQVLQFLISHSDTIQAILRCQDVSAGSLQELALLTGIISKAALPGILSELDVDVNEGSLMELQGHIGRFQRQCLGLLSRFGGSDRLRQFKFQDDNVEGDKVSKKDEIELAMQQICANVMEYCQSLMLQSSPTFQHAVCLFTPSLSETVNRDGPRQDTQAPVVPYWRLPGLGIIIYLLKQSANDFFSYYDSHRQSVSKLQNVEQLPPDEIKELCQSVMPAGVDKISTAQKYVLARRRLVKVINNRAKLLSLCSFIIETCLFILWRHLEYYLLHCMPTDSQDSLFASRTLFKSRRLQDSFASETNLDFRSGLAIVSQHDLDQLQADAINAFGESLQKKLLDIEGLYSKVRSRYSFIQALVRRIRGLLRISRN

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Dog
100
Pig
88
Horse
88
Bovine
88
Sheep
88
Xenopus
88
Chicken
88
Rabbit
88
Zebrafish
67
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q92621 基板として

Site PTM Type Enzyme
A2 Acetylation
T3 Phosphorylation
K18 Ubiquitination
K23 Ubiquitination
K41 Ubiquitination
K55 Ubiquitination
K66 Ubiquitination
K69 Ubiquitination
T72 Phosphorylation
K139 Sumoylation
K147 Sumoylation
K147 Ubiquitination
K156 Ubiquitination
K201 Ubiquitination
K215 Ubiquitination
S218 Phosphorylation
K222 Ubiquitination
K304 Ubiquitination
K321 Ubiquitination
T328 Phosphorylation
S434 Phosphorylation
Y450 Phosphorylation
K451 Ubiquitination
K496 Ubiquitination
K571 Ubiquitination
S575 Phosphorylation
Y581 Phosphorylation
K648 Ubiquitination
T649 Phosphorylation
K655 Ubiquitination
Y833 Phosphorylation
T890 Phosphorylation
K892 Ubiquitination
Y902 Phosphorylation
Y904 Phosphorylation
T908 Phosphorylation
K918 Ubiquitination
S942 Phosphorylation
S970 Phosphorylation
K1013 Ubiquitination
K1042 Ubiquitination
K1150 Ubiquitination
Y1152 Phosphorylation
S1153 Phosphorylation
S1165 Phosphorylation
S1167 Phosphorylation
K1177 Ubiquitination
K1219 Ubiquitination
T1225 Phosphorylation
K1230 Ubiquitination
K1271 Ubiquitination
K1279 Ubiquitination
K1446 Ubiquitination
K1461 Ubiquitination
S1505 Phosphorylation
K1548 Ubiquitination
K1565 Ubiquitination
S1666 Phosphorylation
K1732 Ubiquitination
K1742 Ubiquitination
T1799 Phosphorylation
K1839 Ubiquitination
K1865 Ubiquitination
T1868 Phosphorylation
K1871 Ubiquitination
K1881 Ubiquitination
K1932 Methylation
S1939 Phosphorylation
S1942 Phosphorylation
T1944 Phosphorylation
K1977 Ubiquitination
K1978 Ubiquitination
Y1986 Phosphorylation
K1988 Ubiquitination

研究背景

機能:

Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor NUP62 and other nucleoporins, but not NUP153 and TPR, to the NPC.

細胞の位置付け:

Nucleus membrane>Peripheral membrane protein. Nucleus>Nuclear pore complex.
Note: Localized near the center, on both the cytoplasmic and nuclear side, of the NPC core structure.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Part of the nuclear pore complex (NPC). Forms a complex with NUP35, NUP93, NUP155 and lamin B. Does not interact with TPR.

タンパク質ファミリー:

Belongs to the NUP186/NUP192/NUP205 family.

研究領域

· Genetic Information Processing > Translation > RNA transport.

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