製品: NUP88 Antibody
カタログ: DF9711
タンパク質の説明: Rabbit polyclonal antibody to NUP88
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse
予測: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
分子量: 84 kDa,100kDa; 84kD(Calculated).
ユニプロット: Q99567
RRID: AB_2842906

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
予測:
Pig(90%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(90%)
クローナリティ:
Polyclonal
特異性:
NUP88 Antibody detects endogenous levels of total NUP88.
RRID:
AB_2842906
引用形式: Affinity Biosciences Cat# DF9711, RRID:AB_2842906.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

88 kDa nucleoporin; karyoporin; Nuclear pore complex protein 88; Nuclear pore complex protein Nup88; Nuclear pore complex protein88; Nucleoporin 88; Nucleoporin 88 kDa; Nucleoporin 88kDa; Nucleoporin Nup88; Nucleoporin88; Nucleoporin88kDa; Nup 84; NUP 88; Nup84; NUP88; NUP88_HUMAN; Prei 2; Prei2; Preimplantation protein 2; Preimplantation protein2;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q99567 NUP88_HUMAN:

Ubiquitous.

タンパク質配列:
MAAAEGPVGDGELWQTWLPNHVVFLRLREGLKNQSPTEAEKPASSSLPSSPPPQLLTRNVVFGLGGELFLWDGEDSSFLVVRLRGPSGGGEEPALSQYQRLLCINPPLFEIYQVLLSPTQHHVALIGIKGLMVLELPKRWGKNSEFEGGKSTVNCSTTPVAERFFTSSTSLTLKHAAWYPSEILDPHVVLLTSDNVIRIYSLREPQTPTNVIILSEAEEESLVLNKGRAYTASLGETAVAFDFGPLAAVPKTLFGQNGKDEVVAYPLYILYENGETFLTYISLLHSPGNIGKLLGPLPMHPAAEDNYGYDACAVLCLPCVPNILVIATESGMLYHCVVLEGEEEDDHTSEKSWDSRIDLIPSLYVFECVELELALKLASGEDDPFDSDFSCPVKLHRDPKCPSRYHCTHEAGVHSVGLTWIHKLHKFLGSDEEDKDSLQELSTEQKCFVEHILCTKPLPCRQPAPIRGFWIVPDILGPTMICITSTYECLIWPLLSTVHPASPPLLCTREDVEVAESPLRVLAETPDSFEKHIRSILQRSVANPAFLKASEKDIAPPPEECLQLLSRATQVFREQYILKQDLAKEEIQRRVKLLCDQKKKQLEDLSYCREERKSLREMAERLADKYEEAKEKQEDIMNRMKKLLHSFHSELPVLSDSERDMKKELQLIPDQLRHLGNAIKQVTMKKDYQQQKMEKVLSLPKPTIILSAYQRKCIQSILKEEGEHIREMVKQINDIRNHVNF

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Horse
100
Bovine
100
Sheep
100
Dog
100
Rabbit
100
Pig
90
Chicken
90
Xenopus
70
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q99567 基板として

Site PTM Type Enzyme
A2 Acetylation
S35 Phosphorylation
T37 Phosphorylation
K41 Ubiquitination
S45 Phosphorylation
S46 Phosphorylation
S49 Phosphorylation
S50 Phosphorylation
T57 Phosphorylation
S96 Phosphorylation
K138 Ubiquitination
K142 Ubiquitination
K150 Ubiquitination
C155 S-Nitrosylation
T166 Phosphorylation
S167 Phosphorylation
S168 Phosphorylation
T169 Phosphorylation
S170 Phosphorylation
T209 Phosphorylation
S221 Phosphorylation
K226 Ubiquitination
T231 Phosphorylation
S233 Phosphorylation
S379 Phosphorylation
S387 Phosphorylation
K394 Ubiquitination
K400 Ubiquitination
K426 Ubiquitination
S430 Phosphorylation
K435 Ubiquitination
S437 Phosphorylation
S442 Phosphorylation
T443 Phosphorylation
K456 Ubiquitination
S496 Phosphorylation
T497 Phosphorylation
S517 Phosphorylation
T525 Phosphorylation
S528 Phosphorylation
K531 Ubiquitination
S540 Phosphorylation
K548 Ubiquitination
K552 Ubiquitination
K579 Ubiquitination
K584 Acetylation
K584 Ubiquitination
K592 Acetylation
K592 Ubiquitination
K598 Ubiquitination
K600 Ubiquitination
S606 Phosphorylation
K625 Ubiquitination
K630 Ubiquitination
K642 Ubiquitination
S646 Phosphorylation
S655 Phosphorylation
K663 Ubiquitination
K680 Ubiquitination
Y688 Phosphorylation
K692 Ubiquitination
K695 Ubiquitination
K712 Ubiquitination
K719 Ubiquitination
K730 Ubiquitination

研究背景

機能:

Component of nuclear pore complex.

細胞の位置付け:

Nucleus>Nuclear pore complex.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Ubiquitous.

サブユニット構造:

Interacts with NUP214/CAN. Interacts with NUP62 and NUP98.

研究領域

· Genetic Information Processing > Translation > RNA transport.

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