P2RX1 Antibody - #DF9728
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| 製品: | P2RX1 Antibody |
| カタログ: | DF9728 |
| タンパク質の説明: | Rabbit polyclonal antibody to P2RX1 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 45 kDa; 45kD(Calculated). |
| ユニプロット: | P51575 |
| RRID: | AB_2842923 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF9728, RRID:AB_2842923.
折りたたみ／展開
ATP receptor; H.sapiens mRNA for ATP receptor; P2 RX1; P2rx1; P2RX1 protein; P2RX1_HUMAN; P2X purinoceptor 1; P2X receptor subunit 1; P2X1; P2X1 receptor; Purinergic receptor; Purinergic receptor P2X ligand gated ion channel 1; Purinergic receptor P2X1;
免疫原
- P51575 P2RX1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MARRFQEELAAFLFEYDTPRMVLVRNKKVGVIFRLIQLVVLVYVIGWVFLYEKGYQTSSGLISSVSVKLKGLAVTQLPGLGPQVWDVADYVFPAQGDNSFVVMTNFIVTPKQTQGYCAEHPEGGICKEDSGCTPGKAKRKAQGIRTGKCVAFNDTVKTCEIFGWCPVEVDDDIPRPALLREAENFTLFIKNSISFPRFKVNRRNLVEEVNAAHMKTCLFHKTLHPLCPVFQLGYVVQESGQNFSTLAEKGGVVGITIDWHCDLDWHVRHCRPIYEFHGLYEEKNLSPGFNFRFARHFVENGTNYRHLFKVFGIRFDILVDGKAGKFDIIPTMTTIGSGIGIFGVATVLCDLLLLHILPKRHYYKQKKFKYAEDMGPGAAERDLAATSSTLGLQENMRTS
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P51575 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y16 | Phosphorylation | Uniprot | |
| T18 | Phosphorylation | Uniprot | |
| S130 | Phosphorylation | Uniprot | |
| K138 | Acetylation | Uniprot | |
| Y274 | Phosphorylation | Uniprot | |
| S286 | Phosphorylation | Uniprot | |
| Y370 | Phosphorylation | Uniprot | |
| T386 | Phosphorylation | Uniprot | |
| S387 | Phosphorylation | Uniprot | |
| S388 | Phosphorylation | Uniprot | |
| T389 | Phosphorylation | Uniprot | |
| T398 | Phosphorylation | Uniprot | |
| S399 | Phosphorylation | Uniprot |
研究背景
Ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Seems to be linked to apoptosis, by increasing the intracellular concentration of calcium in the presence of ATP, leading to programmed cell death (By similarity).
Membrane>Multi-pass membrane protein.
Homo- or heteropolymers.
Belongs to the P2X receptor family.
研究領域
· Environmental Information Processing > Signal transduction > Calcium signaling pathway. (View pathway)
· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.
· Organismal Systems > Immune system > Platelet activation. (View pathway)
参考文献
Application: WB Species: Human Sample: breast cancer cell
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