PIGW Antibody - #DF9749
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF9749, RRID:AB_2842944.
折りたたみ／展開
Phosphatidylinositol-glycan biosynthesis class W protein; PIG-W; Pigw; PIGW_HUMAN;
免疫原
- Q7Z7B1 PIGW_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSEKQMKEAFVSNLNGTTVLEITQGLCFPAFCILCRGFLIIFSQYLCSFSPTWKTRFLTDFVVLIVPMVATLTIWASFILLELLGVIIFGAGLLYQIYRRRTCYARLPFLKILEKFLNISLESEYNPAISCFRVITSAFTAIAILAVDFPLFPRRFAKTELYGTGAMDFGVGGFVFGSAMVCLEVRRRKYMEGSKLHYFTNSLYSVWPLVFLGIGRLAIIKSIGYQEHLTEYGVHWNFFFTIIVVKLITPLLLIIFPLNKSWIIALGITVLYQLALDFTSLKRLILYGTDGSGTRVGLLNANREGIISTLGYVAIHMAGVQTGLYMHKNRSHIKDLIKVACFLLLAAISLFISLYVVQVNVEAVSRRMANLAFCIWIVASSLILLSSLLLGDIILSFAKFLIKGALVPCSWKLIQSPVTNKKHSESLVPEAERMEPSLCLITALNRKQLIFFLLSNITTGLINLMVDTLHSSTLWALFVVNLYMFSNCLIVYVLYLQDKTVQFW
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q7Z7B1 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T59 | Phosphorylation | Uniprot | |
| T71 | Phosphorylation | Uniprot | |
| K111 | Ubiquitination | Uniprot | |
| Y287 | Phosphorylation | Uniprot | |
| S292 | Phosphorylation | Uniprot | |
| T294 | Phosphorylation | Uniprot | |
| K412 | Ubiquitination | Uniprot | |
| S416 | Phosphorylation | Uniprot | |
| K421 | Ubiquitination | Uniprot |
研究背景
Required for the transport of GPI-anchored proteins to the plasma membrane. Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins (By similarity).
Endoplasmic reticulum membrane>Multi-pass membrane protein.
Belongs to the PIGW family.
研究領域
· Metabolism > Glycan biosynthesis and metabolism > Glycosylphosphatidylinositol (GPI)-anchor biosynthesis.
· Metabolism > Global and overview maps > Metabolic pathways.
Restrictive clause
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