RAB11FIP5 Antibody - #DF9796
| 製品: | RAB11FIP5 Antibody |
| カタログ: | DF9796 |
| タンパク質の説明: | Rabbit polyclonal antibody to RAB11FIP5 |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat, Monkey |
| 予測: | Pig, Bovine, Horse, Dog |
| 分子量: | 70 kDa; 70kD(Calculated). |
| ユニプロット: | Q9BXF6 |
| RRID: | AB_2842990 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF9796, RRID:AB_2842990.
折りたたみ／展開
GAF 1; Gaf-1; GAF1; gamma SNAP associated factor 1; Gamma-SNAP-associated factor 1; KIAA0857; Phosphoprotein pp75; pp75; RAB11 family interacting protein 5 (class I); Rab11 family-interacting protein 5; Rab11 FIP5; Rab11 interacting protein; Rab11 interacting protein Rip11; Rab11-FIP5; Rab11-interacting protein Rip11; Rab11fip5; RFIP5_HUMAN; RIP11;
免疫原
Detected at low levels in heart, brain, placenta, lung, liver, adipocytes, kidney, spleen, skeletal muscle and pancreas.
- Q9BXF6 RFIP5_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MALVRGAEPAAGPSRWLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVVEKTHGCPEWREECSFELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGVDKFLGQATVALDEVFGAGRAQHTQWYKLHSKPGKKEKERGEIEVTIQFTRNNLSASMFDLSMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKGFFLRNKLRKSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLFTHKRTYSDEANQMRVAPPRALLDLQGHLDAASRSSLCVNGSHIYNEEPQGPVRHRSSISGSLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHPGEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRRSSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDPTQKPSPHPVKPLSAAPVEGSPDRKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQMVDTKRLKDSAVLDQSAKYYHLTHDELISLLLQRERELSQRDEHVQELESYIDRLLVRIMETSPTLLQIPPGPPK
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9BXF6 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| R5 | Methylation | Uniprot | |
| S116 | Phosphorylation | Uniprot | |
| T165 | Phosphorylation | Uniprot | |
| S174 | Phosphorylation | Uniprot | |
| S176 | Phosphorylation | Uniprot | |
| S181 | Phosphorylation | Uniprot | |
| S188 | Phosphorylation | Uniprot | |
| S191 | Phosphorylation | Uniprot | |
| S207 | Phosphorylation | Uniprot | |
| S209 | Phosphorylation | Uniprot | |
| S224 | Phosphorylation | Uniprot | |
| K232 | Methylation | Uniprot | |
| S254 | Phosphorylation | Uniprot | |
| T276 | Phosphorylation | Uniprot | |
| S278 | Phosphorylation | Uniprot | |
| S280 | Phosphorylation | Uniprot | |
| S282 | Phosphorylation | Uniprot | |
| S283 | Phosphorylation | Uniprot | |
| S286 | Phosphorylation | Uniprot | |
| T287 | Phosphorylation | Uniprot | |
| S293 | Phosphorylation | Uniprot | |
| S296 | Phosphorylation | Uniprot | |
| T305 | Phosphorylation | Uniprot | |
| Y306 | Phosphorylation | Uniprot | |
| S307 | Phosphorylation | Q15208 (STK38) | Uniprot |
| S332 | Phosphorylation | Uniprot | |
| S341 | Phosphorylation | Uniprot | |
| Y344 | Phosphorylation | Uniprot | |
| S356 | Phosphorylation | Uniprot | |
| S357 | Phosphorylation | Uniprot | |
| S359 | Phosphorylation | Uniprot | |
| S361 | Phosphorylation | Uniprot | |
| S364 | Phosphorylation | Uniprot | |
| S365 | Phosphorylation | Uniprot | |
| S367 | Phosphorylation | Uniprot | |
| S372 | Phosphorylation | Uniprot | |
| S373 | Phosphorylation | Uniprot | |
| S376 | Phosphorylation | Uniprot | |
| S391 | Phosphorylation | Uniprot | |
| S393 | Phosphorylation | Uniprot | |
| S395 | Phosphorylation | Uniprot | |
| S396 | Phosphorylation | Uniprot | |
| S397 | Phosphorylation | Uniprot | |
| S418 | Phosphorylation | Uniprot | |
| T438 | Phosphorylation | Uniprot | |
| S473 | Phosphorylation | Uniprot | |
| S481 | Phosphorylation | Uniprot | |
| S482 | Phosphorylation | Uniprot | |
| S494 | Phosphorylation | Uniprot | |
| S498 | Phosphorylation | Uniprot | |
| S499 | Phosphorylation | Uniprot | |
| S500 | Phosphorylation | Uniprot | |
| T519 | Phosphorylation | Uniprot | |
| S523 | Phosphorylation | Uniprot | |
| S538 | Phosphorylation | Uniprot | |
| S544 | Phosphorylation | Uniprot | |
| S547 | Phosphorylation | Uniprot | |
| S549 | Phosphorylation | Uniprot | |
| S553 | Phosphorylation | Uniprot | |
| K558 | Ubiquitination | Uniprot | |
| K560 | Ubiquitination | Uniprot | |
| S564 | Phosphorylation | Uniprot | |
| K583 | Ubiquitination | Uniprot | |
| K586 | Ubiquitination | Uniprot | |
| S588 | Phosphorylation | Uniprot | |
| S628 | Phosphorylation | Uniprot | |
| Y629 | Phosphorylation | Uniprot |
研究背景
Rab effector involved in protein trafficking from apical recycling endosomes to the apical plasma membrane. Involved in insulin granule exocytosis. May regulate V-ATPase intracellular transport in response to extracellular acidosis.
Phosphorylated on serine and threonine residues. Phosphorylation at Ser-357 is PKA-dependent.
Cytoplasm. Recycling endosome membrane>Peripheral membrane protein. Early endosome membrane>Peripheral membrane protein. Golgi apparatus membrane>Peripheral membrane protein. Cytoplasmic vesicle>Secretory vesicle membrane>Peripheral membrane protein. Mitochondrion membrane>Peripheral membrane protein.
Detected at low levels in heart, brain, placenta, lung, liver, adipocytes, kidney, spleen, skeletal muscle and pancreas.
Forms a heterooligomeric complex with RAB11FIP4. Binds NAPG and TROVE2. Binds RAB11A that has been activated by GTP binding.
Binds to vesicles enriched in neutral phospholipids via its C2 domain. The interaction is favored by Mg(2+) rather than Ca(2+).
研究領域
· Cellular Processes > Transport and catabolism > Endocytosis. (View pathway)
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