RAB22A Antibody - #DF9820
| 製品: | RAB22A Antibody |
| カタログ: | DF9820 |
| タンパク質の説明: | Rabbit polyclonal antibody to RAB22A |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| 分子量: | 22 kDa; 22kD(Calculated). |
| ユニプロット: | Q9UL26 |
| RRID: | AB_2843014 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF9820, RRID:AB_2843014.
折りたたみ／展開
3732413A17Rik; AI662177; AW319644; AW550514; E130120E14Rik; GTP binding protein RAB22A; MGC16770; OTTMUSP00000017605; Rab 22; RAB 22A; Rab-22; Rab22; RAB22A; RAB22A member RAS oncogene family; Ras related protein Rab 22A; Ras related protein Rab22A; Ras-related protein Rab-22A; RB22A_HUMAN;
免疫原
- Q9UL26 RB22A_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MALRELKVCLLGDTGVGKSSIVWRFVEDSFDPNINPTIGASFMTKTVQYQNELHKFLIWDTAGQERFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWVKELRQHGPPNIVVAIAGNKCDLIDVREVMERDAKDYADSIHAIFVETSAKNAININELFIEISRRIPSTDANLPSGGKGFKLRRQPSEPKRSCC
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9UL26 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K7 | Ubiquitination | Uniprot | |
| T14 | Phosphorylation | Uniprot | |
| S19 | Phosphorylation | Uniprot | |
| S20 | Phosphorylation | Uniprot | |
| K101 | Acetylation | Uniprot | |
| K101 | Ubiquitination | Uniprot | |
| S175 | Phosphorylation | Uniprot |
研究背景
Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes. Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth. Binds GTP and GDP and has low GTPase activity. Alternates between a GTP-bound active form and a GDP-bound inactive form.
Endosome membrane>Lipid-anchor. Cell membrane>Lipid-anchor. Early endosome. Late endosome. Cell projection>Ruffle. Cytoplasmic vesicle. Cytoplasmic vesicle>Phagosome. Cytoplasmic vesicle>Phagosome membrane>Lipid-anchor>Cytoplasmic side.
Note: Recruited to phagosomes containing S.aureus or M.tuberculosis.
Interacts directly with ZFYVE20 (By similarity). Binds EEA1 (By similarity). Interacts (in its GTP-bound form) with RABGEF1. Interacts (in its GTP-bound form) with RINL.
Belongs to the small GTPase superfamily. Rab family.
研究領域
· Cellular Processes > Transport and catabolism > Endocytosis. (View pathway)
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