製品: RAB33B Antibody
カタログ: DF9826
タンパク質の説明: Rabbit polyclonal antibody to RAB33B
アプリケーション: WB IHC
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Horse, Sheep, Dog, Chicken
分子量: 26 kDa; 26kD(Calculated).
ユニプロット: Q9H082
RRID: AB_2843020

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 100ul $280 在庫あり
 200ul $350 在庫あり

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Dog(100%), Chicken(89%)
クローナリティ:
Polyclonal
特異性:
RAB33B Antibody detects endogenous levels of total RAB33B.
RRID:
AB_2843020
引用形式: Affinity Biosciences Cat# DF9826, RRID:AB_2843020.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

DKFZP434G099; MGC138182; RAB 33B; RAB33B; RAB33B member RAS oncogene family; Ras related protein Rab 33B; Ras related protein Rab33B; Ras-associated protein RAB33B; Ras-related protein Rab-33B; RB33B_HUMAN; SMC2;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MAEEMESSLEASFSSSGAVSGASGFLPPARSRIFKIIVIGDSNVGKTCLTYRFCAGRFPDRTEATIGVDFRERAVEIDGERIKIQLWDTAGQERFRKSMVQHYYRNVHAVVFVYDMTNMASFHSLPSWIEECKQHLLANDIPRILVGNKCDLRSAIQVPTDLAQKFADTHSMPLFETSAKNPNDNDHVEAIFMTLAHKLKSHKPLMLSQPPDNGIILKPEPKPAMTCWC

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Chicken
89
Xenopus
67
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9H082 基板として

Site PTM Type Enzyme
T89 Phosphorylation
S98 Phosphorylation
K149 Ubiquitination
K165 Ubiquitination

研究背景

機能:

Protein transport. Acts, in coordination with RAB6A, to regulate intra-Golgi retrograde trafficking. It is involved in autophagy, acting as a modulator of autophagosome formation.

細胞の位置付け:

Golgi apparatus membrane>Lipid-anchor. Golgi apparatus>cis-Golgi network.
Note: Under starvation conditions punctate RAB33B-positive structures are often observed in the cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Interacts with ATG16L. Interaction with ATG16L is important for autophagosome formation (By similarity). Interacts with RIC1 (via C-terminus domain); the interaction is direct with a preference for RAB33B-GTP. Interacts with RGP1.

タンパク質ファミリー:

Belongs to the small GTPase superfamily. Rab family.

研究領域

· Cellular Processes > Transport and catabolism > Autophagy - animal.   (View pathway)

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