製品: RAB9B Antibody
カタログ: DF9838
タンパク質の説明: Rabbit polyclonal antibody to RAB9B
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Horse, Sheep, Rabbit, Dog
分子量: 23 kDa; 23kD(Calculated).
ユニプロット: Q9NP90
RRID: AB_2843032

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%)
クローナリティ:
Polyclonal
特異性:
RAB9B Antibody detects endogenous levels of total RAB9B.
RRID:
AB_2843032
引用形式: Affinity Biosciences Cat# DF9838, RRID:AB_2843032.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

RAB 9B; RAB 9L; Rab-9-like protein; Rab-9L; RAB9 like protein; Rab9b; RAB9B_HUMAN; RAB9L; Ras related protein Rab9B; Ras-related protein Rab-9B;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q9NP90 RAB9B_HUMAN:

Ubiquitous.

タンパク質配列:
MSGKSLLLKVILLGDGGVGKSSLMNRYVTNKFDSQAFHTIGVEFLNRDLEVDGRFVTLQIWDTAGQERFKSLRTPFYRGADCCLLTFSVDDRQSFENLGNWQKEFIYYADVKDPEHFPFVVLGNKVDKEDRQVTTEEAQTWCMENGDYPYLETSAKDDTNVTVAFEEAVRQVLAVEEQLEHCMLGHTIDLNSGSKAGSSCC

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Rabbit
100
Zebrafish
78
Chicken
64
Xenopus
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9NP90 基板として

Site PTM Type Enzyme
K4 Ubiquitination
K20 Ubiquitination
T63 Phosphorylation
T86 Phosphorylation
S88 Phosphorylation
S94 Phosphorylation
K103 Ubiquitination
Y107 Phosphorylation
Y108 Phosphorylation

研究背景

機能:

Involved in the transport of proteins between the endosomes and the trans Golgi network.

細胞の位置付け:

Cell membrane>Lipid-anchor>Cytoplasmic side. Cytoplasmic vesicle>Phagosome. Cytoplasmic vesicle>Phagosome membrane>Lipid-anchor>Cytoplasmic side.
Note: Recruited to phagosomes containing S.aureus or M.tuberculosis.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Ubiquitous.

サブユニット構造:

Interacts (GTP-bound form) with SGSM1; the GDP-bound form has much lower affinity for SGSM1. The GTP-bound form but not the GDP-bound form interacts with HPS4 and the BLOC-3 complex (heterodimer of HPS1 and HPS4) but does not interact with HPS1 alone.

タンパク質ファミリー:

Belongs to the small GTPase superfamily. Rab family.

研究領域

· Human Diseases > Infectious diseases: Viral > Measles.

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